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Discharge of Confirmed Covid-19 Patients Based on Who or Regional Criteria? a Cohort Study Publisher Pubmed



Adeli SH1 ; Parham M2 ; Asghari A2 ; Bagherzade M2 ; Shajari R2 ; Tabarraii R2 ; Shakeri M2 ; Jabbari A2 ; Jafari S3, 4 ; Ahmadpour S3 ; Habibi MA2, 5 ; Khodadai J2 ; Shafiee H2 ; Eskandari N6 Show All Authors
Authors
  1. Adeli SH1
  2. Parham M2
  3. Asghari A2
  4. Bagherzade M2
  5. Shajari R2
  6. Tabarraii R2
  7. Shakeri M2
  8. Jabbari A2
  9. Jafari S3, 4
  10. Ahmadpour S3
  11. Habibi MA2, 5
  12. Khodadai J2
  13. Shafiee H2
  14. Eskandari N6
  15. Dameshghi DO2
  16. Masoumi M2
  17. Ghomi SYF2
  18. Ebrazeh A7
  19. Vafaeimanesh J3
Show Affiliations
Authors Affiliations
  1. 1. Department of Internal Medicine, School of Medicine, Qom University of Medical Sciences, Qom, Iran
  2. 2. Clinical Research Development Center, Qom University of Medical Sciences, Qom, Iran
  3. 3. Gastroenterology and Hepatology Diseases Research Center, Qom University of Medical Sciences, Qom, Iran
  4. 4. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Iranian Tissue Bank & Research Center, Gene, Cell & Tissue Research Institute, Tehran University of Medical Science, Tehran, Iran
  6. 6. Department of Midwifery, School of Nursing and Midwifery, Qom University of Medical Sciences, Qom, Iran
  7. 7. Department of Public Health, Faculty of Health, Qom University of Medical Sciences, Qom, Iran

Source: Infectious Disorders - Drug Targets Published:2023


Abstract

Background: Increasing the number of COVID-19 patients raises concerns about the capacity of the health care system. This issue emphasizes reducing the admission rate and expediting patient discharge. Objective: This study aimed to develop a discharge protocol for COVID-19 patients based on the existing capacity of the healthcare system and to assess its post-discharge outcomes. Methods: This is a multicenter cohort study. All COVID-19 patients referred to selected medical centers in Qom, Iran, from Feb. 19 to Apr. 19, 2020, were target populations. Eligible patients were classi-fied into a) the criterion group and b) the non-criterion group. Patients were followed up daily for 14 days after discharge by phone, and the required data was gathered and recorded in follow-up form. Univariate (chi-square and t-tests) and multivariate multiple (multivariate probit regression) analysis were used. Results: A total of 2775 patients were included in the study (1440 people in the criterion group and 1335 in the non-criterion group). Based on multivariate probit regression, death was statistically associated with discharge outside our criteria (p<0.001), rising age (p<0.001), and being male (p=0.019), and readmission were associated with discharge outside our criteria (p<0.001), rising age (p=0.009), and having the history of underlying diseases (p=0.003). Furthermore, remission had statistically significant associations with discharge based on our criteria (p<0.001), decreasing age (p=0.001), and lack of a history of underlying diseases (p<0.001). Conclusion: Mortality and readmission were significantly lower according to our discharge criteria. Our designed criteria apply to less developed and developing countries due to the limited capacity and resources available in the health care system. © 2023 Bentham Science Publishers.
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