Nanoemulsions for Intravenous Drug Delivery

Nanoemulsions for Intravenous Drug Delivery Publisher

Norouzi P¹ ; Rastegari A² ; Mottaghitalab F³ ; Farokhi M⁴ ; Zarrintaj P^{5, 6} ; Saeb MR⁷

Show Affiliations

1. Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
3. Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4. National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran
5. Polymer Engineering Department, Faculty of Engineering, Urmia University, Urmia, Iran
6. School of Chemical Engineering, Oklahoma State University, Stillwater, OK, United States
7. Department of Resin and Additives, Institute for Color Science and Technology, Tehran, Iran

Source: Nanoengineered Biomaterials for Advanced Drug Delivery Published:2020

Abstract

Nanoemulsions are defined as the heterogeneous dispersion of two immiscible liquids (oil in water or water in oil) with a mean droplet size in range of 20-200ŉm that can be stabilized by different surfactants. Nanoemulsions are prepared by spontaneous emulsification method and high-energy emulsification methods mediated by high-pressure homogenizers and ultrasound generators. Nanoemulsions are considered as an attractive drug delivery system that is applicable for different administration routs including oral, parenteral, and transdermal. Recently, nanoemulsions gained more attention for intravenous delivery of wide variety of drugs due to their favorable properties such as biocompatibility, large surface area, improving the solubility of lipophilic drugs, enhanced pharmacokinetic parameters, drug delivery to targeted tissues by passive and/or active targeting, reduced toxicity, and the ability to alleviate the tumor drug resistance. In this chapter, after describing the characteristics of nanoemulsions, their structural and functional properties in intravenous administration for various drugs are described in detail. © 2020 Elsevier Ltd All rights reserved.

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Style	Citing Format
MLA	Norouzi P, et al.. "Nanoemulsions for Intravenous Drug Delivery." Nanoengineered Biomaterials for Advanced Drug Delivery, vol. , no. , 2020, pp. 581-601.
APA	Norouzi P, Rastegari A, Mottaghitalab F, Farokhi M, Zarrintaj P, Saeb MR (2020). Nanoemulsions for Intravenous Drug Delivery. Nanoengineered Biomaterials for Advanced Drug Delivery, (), 581-601.
Chicago	Norouzi P, Rastegari A, Mottaghitalab F, Farokhi M, Zarrintaj P, Saeb MR. "Nanoemulsions for Intravenous Drug Delivery." Nanoengineered Biomaterials for Advanced Drug Delivery , no. (2020): 581-601.
Harvard	Norouzi P et al. (2020) 'Nanoemulsions for Intravenous Drug Delivery', Nanoengineered Biomaterials for Advanced Drug Delivery, (), pp. 581-601.
Vancouver	Norouzi P, Rastegari A, Mottaghitalab F, Farokhi M, Zarrintaj P, Saeb MR. Nanoemulsions for Intravenous Drug Delivery. Nanoengineered Biomaterials for Advanced Drug Delivery. 2020;():581-601.
BibTex	@article{ author = {Norouzi P and Rastegari A and Mottaghitalab F and Farokhi M and Zarrintaj P and Saeb MR}, title = {Nanoemulsions for Intravenous Drug Delivery}, journal = {Nanoengineered Biomaterials for Advanced Drug Delivery}, volume = {}, number = {}, pages = {581-601}, year = {2020} }
RIS	TY - JOUR AU - Norouzi P AU - Rastegari A AU - Mottaghitalab F AU - Farokhi M AU - Zarrintaj P AU - Saeb MR TI - Nanoemulsions for Intravenous Drug Delivery JO - Nanoengineered Biomaterials for Advanced Drug Delivery VL - IS - SP - 581 EP - 601 PY - 2020 ER -

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