Fabrication of an Electrochemical Sensor Based on Magnetic Multi-Walled Carbon Nanotubes for the Determination of Ciprofloxacin

Fabrication of an Electrochemical Sensor Based on Magnetic Multi-Walled Carbon Nanotubes for the Determination of Ciprofloxacin Publisher

Bagheri H¹ ; Khoshsafar H² ; Amidi S³ ; Hosseinzadeh Ardakani Y⁴

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1. Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
2. Young Researchers and Elite Club, Hamedan Branch, Islamic Azad University, Hamedan, Iran
3. Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4. Biopharmaceutics and Pharmacokinetics Division, Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, 14155-6451, Iran

Source: Analytical Methods Published:2016

Abstract

We have developed a novel and efficient electrochemical sensor to measure ciprofloxacin using a composite of magnetic multi-walled carbon nanotubes (MMWCNTs) and molecularly imprinted polymer (MIP). Magnetic MIP (MMIP) capable of selectively responding to ciprofloxacin was successfully synthesized by a simple method. The characterization of the imprinted composite was carried out by scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The performance of the carbon paste electrode modified with MMIP was investigated using cyclic voltammetry and differential pulse voltammetry to detect ciprofloxacin selectively. The detection limit of this method was determined to be 0.0017 μmol L-1 with a linear detection range (3Sb/m) of 0.005-0.85 μmol L-1. This method proved to be a simple, selective and rapid way of determining ciprofloxacin in pharmaceutical samples and biological fluids. It has potential applications in routine analysis with high specificity, excellent reproducibility, and good stability. © The Royal Society of Chemistry 2016.

Style	Citing Format
MLA	Bagheri H, et al.. "Fabrication of an Electrochemical Sensor Based on Magnetic Multi-Walled Carbon Nanotubes for the Determination of Ciprofloxacin." Analytical Methods, vol. 8, no. 16, 2016, pp. 3383-3390.
APA	Bagheri H, Khoshsafar H, Amidi S, Hosseinzadeh Ardakani Y (2016). Fabrication of an Electrochemical Sensor Based on Magnetic Multi-Walled Carbon Nanotubes for the Determination of Ciprofloxacin. Analytical Methods, 8(16), 3383-3390.
Chicago	Bagheri H, Khoshsafar H, Amidi S, Hosseinzadeh Ardakani Y. "Fabrication of an Electrochemical Sensor Based on Magnetic Multi-Walled Carbon Nanotubes for the Determination of Ciprofloxacin." Analytical Methods 8, no. 16 (2016): 3383-3390.
Harvard	Bagheri H et al. (2016) 'Fabrication of an Electrochemical Sensor Based on Magnetic Multi-Walled Carbon Nanotubes for the Determination of Ciprofloxacin', Analytical Methods, 8(16), pp. 3383-3390.
Vancouver	Bagheri H, Khoshsafar H, Amidi S, Hosseinzadeh Ardakani Y. Fabrication of an Electrochemical Sensor Based on Magnetic Multi-Walled Carbon Nanotubes for the Determination of Ciprofloxacin. Analytical Methods. 2016;8(16):3383-3390.
BibTex	@article{ author = {Bagheri H and Khoshsafar H and Amidi S and Hosseinzadeh Ardakani Y}, title = {Fabrication of an Electrochemical Sensor Based on Magnetic Multi-Walled Carbon Nanotubes for the Determination of Ciprofloxacin}, journal = {Analytical Methods}, volume = {8}, number = {16}, pages = {3383-3390}, year = {2016} }
RIS	TY - JOUR AU - Bagheri H AU - Khoshsafar H AU - Amidi S AU - Hosseinzadeh Ardakani Y TI - Fabrication of an Electrochemical Sensor Based on Magnetic Multi-Walled Carbon Nanotubes for the Determination of Ciprofloxacin JO - Analytical Methods VL - 8 IS - 16 SP - 3383 EP - 3390 PY - 2016 ER -

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