Enhanced Hemocompatibility of a Pegilated Polycarbonate Based Segmented Polyurethane

Enhanced Hemocompatibility of a Pegilated Polycarbonate Based Segmented Polyurethane Publisher

Vakili H¹ ; Mohseni M¹ ; Ghanbari H^{2, 3} ; Yahyaei H¹ ; Makki H¹ ; Gonzalez A⁴ ; Alonsovarona A⁵ ; Garrido Pascual P⁵ ; Irusta L⁴

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1. Department of Polymer and Color Engineering, Amirkabir University of Technology, Tehran, Iran
2. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran
3. Research Center for Advanced Technologies in Cardiovascular Medicine, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences (TUMS), Tehran, Iran
4. POLYMAT, Department of Polymer Science and Technology, University of the Basque Country (UPV/EHU), Donostia-San Sebastian, Spain
5. Department of Cellular Biology and Histology, Faculty of Medicine and Odontology, University of the Basque Country (UPV/EHU), LeioaBizkaia, Spain

Source: International Journal of Polymeric Materials and Polymeric Biomaterials Published:2022

Abstract

The risk of clot formation in blood-contacting devices is a significant concern. Therefore, development of biomaterials with improved hemocompatibility is a clinical need. Altering surface properties is an effective strategy to enhance the hemocompatibility. We have investigated the effect of hydrophilic polyethylene glycol (PEG) amount over the hydrophobic polycarbonate (PC) on hemocompatibility of polyurethanes. The presence of PEG on the surface was evaluated using ATR, AFM, and WCA. At above 20% of PEG to PC ratios, exhibit zero WCA, considerable improvement in hemocompatibility, was achieved. The results indicated the synthesized PUs could be used as coatings of cardiovascular devices. © 2020 Taylor & Francis Group, LLC.

Style	Citing Format
MLA	Vakili H, et al.. "Enhanced Hemocompatibility of a Pegilated Polycarbonate Based Segmented Polyurethane." International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 71, no. 7, 2022, pp. 531-539.
APA	Vakili H, Mohseni M, Ghanbari H, Yahyaei H, Makki H, Gonzalez A, Alonsovarona A, Garrido Pascual P, Irusta L (2022). Enhanced Hemocompatibility of a Pegilated Polycarbonate Based Segmented Polyurethane. International Journal of Polymeric Materials and Polymeric Biomaterials, 71(7), 531-539.
Chicago	Vakili H, Mohseni M, Ghanbari H, Yahyaei H, Makki H, Gonzalez A, Alonsovarona A, Garrido Pascual P, Irusta L. "Enhanced Hemocompatibility of a Pegilated Polycarbonate Based Segmented Polyurethane." International Journal of Polymeric Materials and Polymeric Biomaterials 71, no. 7 (2022): 531-539.
Harvard	Vakili H et al. (2022) 'Enhanced Hemocompatibility of a Pegilated Polycarbonate Based Segmented Polyurethane', International Journal of Polymeric Materials and Polymeric Biomaterials, 71(7), pp. 531-539.
Vancouver	Vakili H, Mohseni M, Ghanbari H, Yahyaei H, Makki H, Gonzalez A, et al.. Enhanced Hemocompatibility of a Pegilated Polycarbonate Based Segmented Polyurethane. International Journal of Polymeric Materials and Polymeric Biomaterials. 2022;71(7):531-539.
BibTex	@article{ author = {Vakili H and Mohseni M and Ghanbari H and Yahyaei H and Makki H and Gonzalez A and Alonsovarona A and Garrido Pascual P and Irusta L}, title = {Enhanced Hemocompatibility of a Pegilated Polycarbonate Based Segmented Polyurethane}, journal = {International Journal of Polymeric Materials and Polymeric Biomaterials}, volume = {71}, number = {7}, pages = {531-539}, year = {2022} }
RIS	TY - JOUR AU - Vakili H AU - Mohseni M AU - Ghanbari H AU - Yahyaei H AU - Makki H AU - Gonzalez A AU - Alonsovarona A AU - Garrido Pascual P AU - Irusta L TI - Enhanced Hemocompatibility of a Pegilated Polycarbonate Based Segmented Polyurethane JO - International Journal of Polymeric Materials and Polymeric Biomaterials VL - 71 IS - 7 SP - 531 EP - 539 PY - 2022 ER -

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