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Pathogenesis, Treatments, and Challenges Associated With Malaria and Nanomedicines for Antimalarial Therapy Publisher



Shamsnia HS1, 2 ; Hosseini Y1, 2 ; Niknejad AH1, 2 ; Momtaz S3, 4 ; Abdolghaffari AH1, 2 ; Jamialahmadi T5 ; Sahebkar A5, 6, 7
Authors
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Authors Affiliations
  1. 1. Department of Toxicology & Pharmacology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  2. 2. GI Pharmacology Interest Group (GPIG), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  3. 3. Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran
  4. 4. Department of Toxicology and Pharmacology, School of Pharmacy, Toxicology and Diseases Group, Pharmaceutical Sciences Research Center (PSRC), The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  6. 6. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
  7. 7. Department of Biotechnology, School of Pharmacy, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

Source: Advances in Antiparasitic Therapies and Drug Delivery Published:2023


Abstract

Malaria has been considered as a life-threatening parasitic infection and is a global major concern. Malaria is caused by Plasmodium sp. and is transmitted by Anopheles mosquito species. Malaria is mostly prevalent in vulnerable and poor countries and have a high morbidity rate. Many approaches have been evaluated and investigated for malaria prevention, treatment, and eradication; however, the majority of them were not efficient. Thus, exploration of new approaches and treatments seems to be necessary. Lately, nanomedicine, the nanotechnology which is used in medicine, has been evaluated in many studies, and there is evidence that nanomedicine can act efficiently for malaria treatment, diagnosis, and, to some extent, eradication. This study aims to investigate the application of nanomedicine in malaria disease. © 2024 Elsevier Inc. All rights reserved.
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