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The Effect of Probiotics on Gestational Diabetes and Its Complications in Pregnant Mother and Newborn: A Systematic Review and Meta-Analysis During 2010–2020 Publisher Pubmed



Mahdizade Ari M1, 2 ; Teymouri S1, 2 ; Fazlalian T3 ; Asadollahi P4 ; Afifirad R5 ; Sabaghan M6 ; Valizadeh F7 ; Ghanavati R6 ; Darbandi A1, 2
Authors
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Authors Affiliations
  1. 1. Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  2. 2. Microbial Biotechnology Research Centre, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Microbial Biotechnology, Tehran Science and Research Branch, Islamic Azad University, Tehran, Iran
  4. 4. Department of Microbiology, Faculty of medicine, Ilam University of Medical Sciences, Ilam, Iran
  5. 5. Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Behbahan Faculty of Medical Sciences, Behbahan, Iran
  7. 7. Department of Endodontics, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Source: Journal of Clinical Laboratory Analysis Published:2022


Abstract

This study was aimed to evaluate the effect of probiotics consumption on gestational diabetes (GD) and its complications in pregnant mother and newborn. The study was registered on PROSPERO (CRD42021243409) and all the enrolled articles were collected from four databases (Medline, Scopus, Embase, and Google Scholar) as randomized controlled trials (RCTs) from 2010 to 2020. A total of 4865 study participants from 28 selected studies were included in this review. The present meta-analysis showed that the consumption of probiotics supplementation has the potential to decrease GD-predisposing metabolic parameters such as blood glucose level, lipid profile, inflammation, and oxidative markers which may reduce GD occurrence among pregnant women. © 2022 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC.
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