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The Prevalence and Genotype Distribution of Adenovirus Respiratory Infection Among Iranian Hajj Pilgrims in 2015 Publisher



Kamalpour R1 ; Shayestehpour M2, 3 ; Shafieijandaghi NZ1 ; Yavarian J1 ; Naseri M1 ; Azad TM1
Authors
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Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, 14716 13151, Iran
  2. 2. Department of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Isfahan, Iran
  3. 3. Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Isfahan, Iran

Source: Future Virology Published:2020


Abstract

Aim: Respiratory viruses are the most common cause of hospitalization of pilgrims during Hajj. This study aimed to detect adenovirus genotypes among Iranian pilgrims with acute respiratory tract infection in Hajj season of 2015. Materials & methods: In this cross-sectional study, throat swab samples of 338 Iranian pilgrims with flu-like symptoms were screened for adenovirus by polymerase chain reaction, and virus genotypes were determined using sequencing method. Results: Seventy-seven cases were positive for adenovirus (22.78%). The adenovirus type 6 was the most frequently detected virus followed by type 5, 1, 2 and 57. Conclusion: The prevalence of adenovirus respiratory infection among Iranian pilgrims is considerable. Preparation and administration of an effective adenovirus vaccine is recommended. © 2020 Future Medicine Ltd.