Inherited Interleukin 2-Inducible T-Cell (Itk) Kinase Deficiency in Siblings With Epidermodysplasia Verruciformis and Hodgkin Lymphoma

Inherited Interleukin 2-Inducible T-Cell (Itk) Kinase Deficiency in Siblings With Epidermodysplasia Verruciformis and Hodgkin Lymphoma Publisher Pubmed

Youssefian L^{1, 2} ; Vahidnezhad H^{1, 4} ; Yousefi M^{5, 6} ; Saeidian AH¹ ; Azizpour A⁷ ; Touati A^{1, 8} ; Nikbakht N¹ ; Hesari KK⁹ ; Adibsereshki MM¹⁰ ; Zeinali S^{4, 11} ; Mansoori B^{12, 13} ; Jazayeri A¹⁴ ; Karamzadeh R¹⁵ ; Fortina P¹⁶ Show All Authors

Youssefian L^{1, 2}
Vahidnezhad H^{1, 4}
Yousefi M^{5, 6}
Saeidian AH¹
Azizpour A⁷
Touati A^{1, 8}
Nikbakht N¹
Hesari KK⁹
Adibsereshki MM¹⁰
Zeinali S^{4, 11}
Mansoori B^{12, 13}
Jazayeri A¹⁴
Karamzadeh R¹⁵
Fortina P¹⁶
Jouanguy E^{17, 18, 19}
Casanova JL^{17, 18, 19, 20, 21}
Uitto J¹

Show Affiliations

1. Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, United States
2. Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Iran
3. Thomas Jefferson University, Philadelphia, PA, United States
4. Biotechnology Research Center, Department of Molecular Medicine, Pasteur Institute of Iran, Tehran, Iran
5. Department of Immunology, Faculty of Medicine, Tehran University of Medical Sciences, Iran
6. Drug Applied Research Center, Tabriz University of Medical Sciences, Iran
7. Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Iran
8. Drexel University, College of Medicine, Philadelphia, PA, United States
9. Department of Pathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
10. Gastrointestinal and Liver Diseases Research Center, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran
11. Kawsar Human Genetics Research Center, Tehran, Iran
12. Immunology Research Center, Tehran, Iran
13. Student Research Committee, Tabriz University of Medical Sciences, Iran
14. Department of Information Science, College of Computing and Informatics, Drexel University, Philadelphia, PA, United States
15. Department of Stem Cells, Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Academic Center for Education, Culture and Research, Tehran, Iran
16. Cancer Genomics and Bioinformatics, Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, United States
17. St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, United States
18. Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Necker Hospital for Sick Children, France
19. Imagine Institute, Paris Descartes University, France
20. Howard Hughes Medical Institute, New York, NY, United States
21. Pediatric Hematology and Immunology Unit, Assistance Publique-Hopitaux de Paris, Necker Hospital for Sick Children, Paris, France

Source: Clinical Infectious Diseases Published:2019

Abstract

Biallelic mutations in the ITK gene cause a T-cell primary immunodeficiency with Epstein-Barr virus (EBV)-lymphoproliferative disorders. We describe a novel association of a homozygous ITK mutation with β-human papillomavirus (HPV)-positive epidermodysplasia verruciformis. Thus, loss of function in ITK can result in broad dysregulation of T-cell responses to oncogenic viruses, including β-HPV and EBV. © The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved.

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Style	Citing Format
MLA	Youssefian L, et al.. "Inherited Interleukin 2-Inducible T-Cell (Itk) Kinase Deficiency in Siblings With Epidermodysplasia Verruciformis and Hodgkin Lymphoma." Clinical Infectious Diseases, vol. 68, no. 11, 2019, pp. 1938-1941.
APA	Youssefian L, Vahidnezhad H, Yousefi M, Saeidian AH, Azizpour A, Touati A, Nikbakht N, Hesari KK, Adibsereshki MM, Zeinali S, Mansoori B, Jazayeri A, Karamzadeh R, Fortina P, Jouanguy E, Casanova JL, Uitto J (2019). Inherited Interleukin 2-Inducible T-Cell (Itk) Kinase Deficiency in Siblings With Epidermodysplasia Verruciformis and Hodgkin Lymphoma. Clinical Infectious Diseases, 68(11), 1938-1941.
Chicago	Youssefian L, Vahidnezhad H, Yousefi M, Saeidian AH, Azizpour A, Touati A, Nikbakht N, et al.. "Inherited Interleukin 2-Inducible T-Cell (Itk) Kinase Deficiency in Siblings With Epidermodysplasia Verruciformis and Hodgkin Lymphoma." Clinical Infectious Diseases 68, no. 11 (2019): 1938-1941.
Harvard	Youssefian L et al. (2019) 'Inherited Interleukin 2-Inducible T-Cell (Itk) Kinase Deficiency in Siblings With Epidermodysplasia Verruciformis and Hodgkin Lymphoma', Clinical Infectious Diseases, 68(11), pp. 1938-1941.
Vancouver	Youssefian L, Vahidnezhad H, Yousefi M, Saeidian AH, Azizpour A, Touati A, et al.. Inherited Interleukin 2-Inducible T-Cell (Itk) Kinase Deficiency in Siblings With Epidermodysplasia Verruciformis and Hodgkin Lymphoma. Clinical Infectious Diseases. 2019;68(11):1938-1941.
BibTex	@article{ author = {Youssefian L and Vahidnezhad H and Yousefi M and Saeidian AH and Azizpour A and Touati A and Nikbakht N and Hesari KK and Adibsereshki MM and Zeinali S and Mansoori B and Jazayeri A and Karamzadeh R and Fortina P and Jouanguy E and Casanova JL and Uitto J}, title = {Inherited Interleukin 2-Inducible T-Cell (Itk) Kinase Deficiency in Siblings With Epidermodysplasia Verruciformis and Hodgkin Lymphoma}, journal = {Clinical Infectious Diseases}, volume = {68}, number = {11}, pages = {1938-1941}, year = {2019} }
RIS	TY - JOUR AU - Youssefian L AU - Vahidnezhad H AU - Yousefi M AU - Saeidian AH AU - Azizpour A AU - Touati A AU - Nikbakht N AU - Hesari KK AU - Adibsereshki MM AU - Zeinali S AU - Mansoori B AU - Jazayeri A AU - Karamzadeh R AU - Fortina P AU - Jouanguy E AU - Casanova JL AU - Uitto J TI - Inherited Interleukin 2-Inducible T-Cell (Itk) Kinase Deficiency in Siblings With Epidermodysplasia Verruciformis and Hodgkin Lymphoma JO - Clinical Infectious Diseases VL - 68 IS - 11 SP - 1938 EP - 1941 PY - 2019 ER -

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