Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma

Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma Publisher Pubmed

Miller HK¹ ; Stoddard RA² ; Dawsey SM³ ; Nasrollahzadeh D⁴ ; Abnet CC³ ; Etemadi A^{3, 4} ; Kamangar F^{4, 5} ; Murphy G³ ; Sotoudeh M⁴ ; Kersh GJ¹ ; Malekzadeh R⁴ ; Camargo MC³

Show Affiliations

1. Rickettsial Zoonoses Branch and Centers for Disease Control and Prevention, Atlanta, Georgia, United States
2. Bacterial Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States
3. Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States
4. Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
5. Department of Biology, School of Computer, Mathematical, and Natural Sciences, Morgan State University, Baltimore, Maryland, United States

Source: Vector-Borne and Zoonotic Diseases Published:2021

Abstract

Questionnaire data have linked contact with ruminants to the risk of esophageal squamous cell carcinoma (ESCC) in high-risk Asian populations. To better understand this observed association, we investigated exposure to two major zoonotic ruminant pathogens relative to ESCC risk. Using enzyme-linked immunosorbent assay, immunofluorescence assay, and Brucella microagglutination test assays, we measured immunoglobulin G anti-Coxiella burnetii and anti-Brucella spp. antibodies in patients with ESCC (n = 177) and population-based controls (n = 177) matched by age, gender, and residence area from the Golestan case-control study in Iran. We found a similarly high seroprevalence of C. burnetii in ESCC cases and controls (75% and 80%, respectively), and a similarly low seroprevalence of Brucella spp. (0% and 0.6%, respectively). While documenting a high exposure to one of two zoonotic ruminant infections, this exposure failed to explain the observed association of ruminant contact and ESCC risk in this high-risk population. © Copyright 2021, Mary Ann Liebert, Inc., publishers 2021.

2. Secondhand Smoking and the Risk of Esophageal Squamous Cell Carcinoma in a High Incidence Region, Kashmir, India: A Case-Control-Observational Study, Medicine (United States) (2016)

3. Current Status and Future Prospects for Esophageal Cancer, Cancers (2023)

Experts (# of related papers)

Reza Malekzadeh (2)

Style	Citing Format
MLA	Miller HK, et al.. "Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma." Vector-Borne and Zoonotic Diseases, vol. 21, no. 2, 2021, pp. 125-127.
APA	Miller HK, Stoddard RA, Dawsey SM, Nasrollahzadeh D, Abnet CC, Etemadi A, Kamangar F, Murphy G, Sotoudeh M, Kersh GJ, Malekzadeh R, Camargo MC (2021). Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma. Vector-Borne and Zoonotic Diseases, 21(2), 125-127.
Chicago	Miller HK, Stoddard RA, Dawsey SM, Nasrollahzadeh D, Abnet CC, Etemadi A, Kamangar F, et al.. "Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma." Vector-Borne and Zoonotic Diseases 21, no. 2 (2021): 125-127.
Harvard	Miller HK et al. (2021) 'Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma', Vector-Borne and Zoonotic Diseases, 21(2), pp. 125-127.
Vancouver	Miller HK, Stoddard RA, Dawsey SM, Nasrollahzadeh D, Abnet CC, Etemadi A, et al.. Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma. Vector-Borne and Zoonotic Diseases. 2021;21(2):125-127.
BibTex	@article{ author = {Miller HK and Stoddard RA and Dawsey SM and Nasrollahzadeh D and Abnet CC and Etemadi A and Kamangar F and Murphy G and Sotoudeh M and Kersh GJ and Malekzadeh R and Camargo MC}, title = {Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma}, journal = {Vector-Borne and Zoonotic Diseases}, volume = {21}, number = {2}, pages = {125-127}, year = {2021} }
RIS	TY - JOUR AU - Miller HK AU - Stoddard RA AU - Dawsey SM AU - Nasrollahzadeh D AU - Abnet CC AU - Etemadi A AU - Kamangar F AU - Murphy G AU - Sotoudeh M AU - Kersh GJ AU - Malekzadeh R AU - Camargo MC TI - Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma JO - Vector-Borne and Zoonotic Diseases VL - 21 IS - 2 SP - 125 EP - 127 PY - 2021 ER -

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