Plant-Based Vaccines and Cancer Therapy: Where Are We Now and Where Are We Going?

Plant-Based Vaccines and Cancer Therapy: Where Are We Now and Where Are We Going? Publisher Pubmed

Rahimian N¹ ; Miraei HR² ; Amiri A³ ; Ebrahimi MS⁴ ; Nahand JS⁵ ; Tarrahimofrad H⁶ ; Hamblin MR⁷ ; Khan H⁸ ; Mirzaei H⁹

Show Affiliations

1. Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran
2. Department of Medical Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashahd, Iran
4. School of Medicine, Kashan University of Medical Sciences, Kashan, Iran
5. Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
6. Department of Animal Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran
7. Laser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, South Africa
8. Department of Pharmacy, Abdul Wali Khan University Mardan, 23200, Pakistan
9. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran

Source: Pharmacological Research Published:2021

Abstract

Therapeutic vaccines are an effective approach in cancer therapy for treating the disease at later stages. The Food and Drug Administration (FDA) recently approved the first therapeutic cancer vaccine, and further studies are ongoing in clinical trials. These are expected to result in the future development of vaccines with relatively improved efficacy. Several vaccination approaches are being studied in pre-clinical and clinical trials, including the generation of anti-cancer vaccines by plant expression systems.This approach has advantages, such as high safety and low costs, especially for the synthesis of recombinant proteins. Nevertheless, the development of anti-cancer vaccines in plants is faced with some technical obstacles.Herein, we summarize some vaccines that have been used in cancer therapy, with an emphasis on plant-based vaccines. © 2021 Elsevier Ltd

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Style	Citing Format
MLA	Rahimian N, et al.. "Plant-Based Vaccines and Cancer Therapy: Where Are We Now and Where Are We Going?." Pharmacological Research, vol. 169, no. , 2021, pp. -.
APA	Rahimian N, Miraei HR, Amiri A, Ebrahimi MS, Nahand JS, Tarrahimofrad H, Hamblin MR, Khan H, Mirzaei H (2021). Plant-Based Vaccines and Cancer Therapy: Where Are We Now and Where Are We Going?. Pharmacological Research, 169(), -.
Chicago	Rahimian N, Miraei HR, Amiri A, Ebrahimi MS, Nahand JS, Tarrahimofrad H, Hamblin MR, Khan H, Mirzaei H. "Plant-Based Vaccines and Cancer Therapy: Where Are We Now and Where Are We Going?." Pharmacological Research 169, no. (2021): -.
Harvard	Rahimian N et al. (2021) 'Plant-Based Vaccines and Cancer Therapy: Where Are We Now and Where Are We Going?', Pharmacological Research, 169(), pp. -.
Vancouver	Rahimian N, Miraei HR, Amiri A, Ebrahimi MS, Nahand JS, Tarrahimofrad H, et al.. Plant-Based Vaccines and Cancer Therapy: Where Are We Now and Where Are We Going?. Pharmacological Research. 2021;169():-.
BibTex	@article{ author = {Rahimian N and Miraei HR and Amiri A and Ebrahimi MS and Nahand JS and Tarrahimofrad H and Hamblin MR and Khan H and Mirzaei H}, title = {Plant-Based Vaccines and Cancer Therapy: Where Are We Now and Where Are We Going?}, journal = {Pharmacological Research}, volume = {169}, number = {}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Rahimian N AU - Miraei HR AU - Amiri A AU - Ebrahimi MS AU - Nahand JS AU - Tarrahimofrad H AU - Hamblin MR AU - Khan H AU - Mirzaei H TI - Plant-Based Vaccines and Cancer Therapy: Where Are We Now and Where Are We Going? JO - Pharmacological Research VL - 169 IS - SP - EP - PY - 2021 ER -

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