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Birth Weight and Risk of Cardiovascular Disease Incidence in Adulthood: A Dose-Response Meta-Analysis Publisher Pubmed



Mohseni R1 ; Mohammed SH2 ; Safabakhsh M3 ; Mohseni F4 ; Monfared ZS5 ; Seyyedi J6 ; Mejareh ZN7 ; Alizadeh S8
Authors
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Authors Affiliations
  1. 1. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  2. 2. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences-International Campus (TUMS-IC), Tehran, Iran
  3. 3. Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  4. 4. School of Medicine, Arak University of Medical Sciences, Arak, Iran
  5. 5. School of Nursing & Midwifery, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  6. 6. Department of Medical Surgical Nursing, School of Nursing & Midwifery, Tehran University of Medical Sciences (TUMS), Tehran, Iran
  7. 7. Student Research Committee, School of Medicine, Iran University of Medical Sciences (TUMS), Tehran, Iran
  8. 8. Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran

Source: Current Atherosclerosis Reports Published:2020


Abstract

Purpose of Review: Studies have revealed a relation between birth weight (BW) and later risk of cardiovascular diseases (CVDs). This meta-analysis aimed to report the dose-response relationship between BW and risk of CVDs. Recent Findings: The relation of BW to CVD subtypes was found to be U-shaped as BW below ~ 2500 g and above ~ 4000 g affected positively CVD risk (OR = 1.14 = 95%CI 1.03–1.27 and OR = 1.08; 95%CI 0.99–1.18, respectively). Regarding CVD subtypes, low BW was directly linked to greater risk of CHD (OR = 1.15; 95%CI 1.02–1.29) and stroke (OR = 1.28; 95% CI 1.05–1.55), while high BW was related to increased risk of arterial fibrillation in adulthood. A U-shaped nonlinear relationship was specifically demonstrated between BW and overall CVD and its subtypes. Summary: There is a U-shaped association between BW and all CVD subtypes. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
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