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Electrochemiluminescence Analysis of Levodopa Using Luminol at Mwcnt-Modified Electrode



Mirzanasiri N1 ; Hosseini M2 ; Larijani B3 ; Rashedi H4
Authors
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Authors Affiliations
  1. 1. Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  2. 2. Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, Tehran, Iran
  3. 3. Endocrinology & Metabolism Research Center, Endocrinology & Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Chemical Engineering, Faculty of Engineering, University of Tehran, Tehran, Iran

Source: Analytical and Bioanalytical Electrochemistry Published:2018

Abstract

Levedopa was sensitively determined based on electrogenerated chemiluminescence (ECL) mechanism through enhancing the weak ECL of electro-oxidized luminal in presence of levodopa, on a multiwall carbon nanotubes (MWCNTs)-modified electrode. Under optimal conditions, the relative ECL emission/levodopa concentration plot was found to be linear from 1.0×10-9 to 1.7×10-7 M and a detection limit of 6.7×10-10 M was recorded. The modified electrode was found applicable to the analysis of levodopa in urine samples. © 2018 by CEE (Center of Excellence in Electrochemistry).