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Application of Fe3o4@Sio2/Mwcnt Film on Glassy Carbon Electrode for the Sensitive Electroanalysis of Levodopa Publisher



Ganjali MR1, 2 ; Salimi H3 ; Tajik S4 ; Beitollahi H4 ; Rezapour M5 ; Larijani B6
Authors
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Authors Affiliations
  1. 1. Center of Excellence in Electrochemistry, School of Chemistry, University of Tehran, Tehran, Iran
  2. 2. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran
  4. 4. Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran
  5. 5. IP Department, Research Institute of the Petroleum Industry (RIPI), P.O. Box 14665-137, Tehran, Iran
  6. 6. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: International Journal of Electrochemical Science Published:2017


Abstract

A Fe3O4@SiO2/MWCNT (FSCNT) film was coated on a glassy carbon electrode, and then electrochemical oxidation behavior of levodopa was considered in PBS (pH 7.0) by cyclic and differential pulse voltammetry (CV and DPV). The obtained results showed that the new electrode has an electrocatalytic activity in oxidation of levodopa which causes a remarkable enhancement in its oxidation current.. In the optimum conditions, the anodic peak current indicated a linear relation versus levodopa concentration in the range of 1.0 × 10-5 to 6.0 × 10-4 M with detection limits of 2.0 × 10-6 M (signal-to-noise = 3). This method was used to the measurement of levodopa in urine samples. © 2017 The Authors.