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Genomic Medicine on the Frontier of Precision Medicine Publisher



Hasanzad M1, 2 ; Sarhangi N2 ; Naghavi A3 ; Ghavimehr E1 ; Khatami F4 ; Ehsani Chimeh S5 ; Larijani B6 ; Aghaei Meybodi HR2
Authors
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Authors Affiliations
  1. 1. Medical Genomics Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  2. 2. Personalized Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, No.10- Jalal -e-Ale-Ahmad Street, Chamran Highway, Tehran, 1411713119, Iran
  3. 3. Cellular and Molecular Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
  4. 4. Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. University of Arizona Cancer Center, Tucson, AZ, United States
  6. 6. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Diabetes and Metabolic Disorders Published:2022


Abstract

Genomic medicine has created a great deal of hope since the completion of the Human Genome Project (HGP). Genomic medicine promises disease prevention and early diagnosis in the context of precision medicine. Precision medicine as a scientific discipline has introduced as an evolution in medicine. The rapid growth of high-development technologies permits the assessment of biological systems. Study of the integrated profiles of omics, such as genome, transcriptome, proteome and other omics information lead to significant advances in personalized and precision medicine. In the context of precision medicine, pharmacogenomics can play an important role in order to discriminate responders and non-responders to medications and avoiding toxicity and achieving the optimum dose. So precision medicine in accordance with genomic medicine will transform medicine from conventional evidence-based medicine in the diagnosis and treatment towards precision based-medicine. In this review, we have summarized the related issues for genomic medicine and precision medicine. © 2021, Springer Nature Switzerland AG.
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