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Recent Strategies in the Synthesis of Thiophene Derivatives: Highlights From the 2012–2020 Literature Publisher Pubmed



Abedinifar F1 ; Babazadeh Rezaei E1 ; Biglar M1 ; Larijani B1 ; Hamedifar H2 ; Ansari S2 ; Mahdavi M1
Authors
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, 14176, Iran
  2. 2. CinnaGen Medical Biotechnology Research Center, Alborz University of Medical Sciences, Karaj, Iran

Source: Molecular Diversity Published:2021


Abstract

Thiophene-based analogs have been fascinated by a growing number of scientists as a potential class of biologically active compounds. Furthermore, they play a vital role for medicinal chemists to improve advanced compounds with a variety of biological effects. The current review envisioned to highlight some recent and particularly remarkable examples of the synthesis of thiophene derivatives by heterocyclization of various substrates from 2012 on. Graphic abstract: [Figure not available: see fulltext.]. © 2020, Springer Nature Switzerland AG.