Detection of Vim- and Imp-Type Metallo-Beta-Lactamase Genes in Acinetobacter Baumannii Isolates From Patients in Two Hospitals in Tehran

Detection of Vim- and Imp-Type Metallo-Beta-Lactamase Genes in Acinetobacter Baumannii Isolates From Patients in Two Hospitals in Tehran Publisher

Davoodi S¹ ; Boroumand MA² ; Sepehriseresht S² ; Pourgholi L²

Show Affiliations

1. Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
2. Department of Molecular Pathology, Tehran Heart Center, Tehran University of Medical Science, Tehran, Iran

Source: Iranian Journal of Biotechnology Published:2015

Abstract

Background: Acinetobacter baumannii, is an opportunistic pathogen and is responsible for numerous nosocomial infections. In recent years, this microorganism has been resistant to a wide range of antibiotics. One of the most important mechanisms of resistance in this microorganism is production of metallo-beta-lactamases (MBLs). Objectives: The aim of this study was to detect VIM- and IMP-type metallo-beta-lactamase genes in Acinetobacter baumanniiisolates from patients in two Hospitals in Tehran. Materials and Methods: 104 isolates were tested using the PCR method for the identification of VIM- and IMP-type genes. Results: vim1, vim2, imp1and imp2 genes were detected in 6.7%, 41.7%, 50% and 1.7% of the isolates from Tehran Heart Center, and in 29.5%, 38.6%, 4.5% and 4.5% of the isolates from Shahid Mutahhari Hospital respectively. Discussion: Our analysis revealed that the majority of the isolates had at least one of these genes, indicating that MBLs production is an important resistance mechanism in Acinetobacter baumannii. © 2015, Kowsar Medical Publishing Company. All rights reserved.

Style	Citing Format
MLA	Davoodi S, et al.. "Detection of Vim- and Imp-Type Metallo-Beta-Lactamase Genes in Acinetobacter Baumannii Isolates From Patients in Two Hospitals in Tehran." Iranian Journal of Biotechnology, vol. 13, no. 1, 2015, pp. 63-67.
APA	Davoodi S, Boroumand MA, Sepehriseresht S, Pourgholi L (2015). Detection of Vim- and Imp-Type Metallo-Beta-Lactamase Genes in Acinetobacter Baumannii Isolates From Patients in Two Hospitals in Tehran. Iranian Journal of Biotechnology, 13(1), 63-67.
Chicago	Davoodi S, Boroumand MA, Sepehriseresht S, Pourgholi L. "Detection of Vim- and Imp-Type Metallo-Beta-Lactamase Genes in Acinetobacter Baumannii Isolates From Patients in Two Hospitals in Tehran." Iranian Journal of Biotechnology 13, no. 1 (2015): 63-67.
Harvard	Davoodi S et al. (2015) 'Detection of Vim- and Imp-Type Metallo-Beta-Lactamase Genes in Acinetobacter Baumannii Isolates From Patients in Two Hospitals in Tehran', Iranian Journal of Biotechnology, 13(1), pp. 63-67.
Vancouver	Davoodi S, Boroumand MA, Sepehriseresht S, Pourgholi L. Detection of Vim- and Imp-Type Metallo-Beta-Lactamase Genes in Acinetobacter Baumannii Isolates From Patients in Two Hospitals in Tehran. Iranian Journal of Biotechnology. 2015;13(1):63-67.
BibTex	@article{ author = {Davoodi S and Boroumand MA and Sepehriseresht S and Pourgholi L}, title = {Detection of Vim- and Imp-Type Metallo-Beta-Lactamase Genes in Acinetobacter Baumannii Isolates From Patients in Two Hospitals in Tehran}, journal = {Iranian Journal of Biotechnology}, volume = {13}, number = {1}, pages = {63-67}, year = {2015} }
RIS	TY - JOUR AU - Davoodi S AU - Boroumand MA AU - Sepehriseresht S AU - Pourgholi L TI - Detection of Vim- and Imp-Type Metallo-Beta-Lactamase Genes in Acinetobacter Baumannii Isolates From Patients in Two Hospitals in Tehran JO - Iranian Journal of Biotechnology VL - 13 IS - 1 SP - 63 EP - 67 PY - 2015 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract