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An Overview of Neuro-Oncology Research and Practice in Iran, Three Years With the Nosc Initiative



Haddad P1 ; Shazadi S2 ; Samiei F1 ; Kharrazi HH3 ; Tabatabaeefar M4 ; Rakhsha A4 ; Faranoosh M5 ; Torabinami M6, 8 ; Dadras A7, 8 ; Liaghi A7, 8 ; Nafarieh L8
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Authors Affiliations
  1. 1. Cancer Institute, Department of Radiation Oncology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Departments of Neurosurgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Department of Radiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  4. 4. Radiation Oncology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. MAHAK Pediatric Cancer Treatment and Research Center (MPCTRC), Tehran, Iran
  6. 6. Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
  7. 7. Institute of Biochemistry and Biophysics (I.B.B.), University of Tehran, Tehran, Iran
  8. 8. Behphar Scientific Committee, Tehran, Iran

Source: International Journal of Clinical and Experimental Medicine Published:2015

Abstract

Research and practice of neuro-oncology compiles clinical neuroscience expertise from neurosurgery, radiation oncology, neuroradiology, medical oncology, neuropathology and related disciplines to optimize planning and therapy in central nervous system malignancies. Such an interdisciplinary context prompted health-care providers from all related disciplines to establish the Neuro-Oncology Scientific Club (NOSC) in Iran and let it flourish since 3 years ago. With the advent of advanced technologies and through continued share of experience, NOSC members have tried to provide more integrated diagnoses and therapeutic care to brain tumor patients across the country. NOSC activities revolve around some key tenets including dissemination of education and updates, facilitation of institutional collaborations; data registry and patients’ awareness. By virtue of recent insights on molecular characterization of brain tumors such as codeletion of chromosomes 1p and 19q in anaplastic gliomas and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in glioblastoma, a range of translational research is being followed within NOSC. The most recent NOSC meeting which was held in Tehran, recapitulated main advances and dealt with the current debates on functional neurosurgery, biological markers and neuroimaging, risk prediction models in high grade gliomas and clinical issues in pediatric neuro-oncology. This article gives an overview of current hotspots in neuro-oncology research and practice which are pursued within NOSC. © 2015, Int J Clin Exp Med. All rights reserved.
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