Exosomal Micrornas Derived From Mesenchymal Stem Cells: Cell-To-Cell Messages

Exosomal Micrornas Derived From Mesenchymal Stem Cells: Cell-To-Cell Messages Publisher Pubmed

Asgarpour K¹ ; Shojaei Z² ; Amiri F³ ; Ai J⁴ ; Mahjoubintehran M^{5, 6} ; Ghasemi F⁷ ; Arefnezhad R⁸ ; Hamblin MR⁹ ; Mirzaei H¹⁰

Show Affiliations

1. Department of Medicine, University of Western Ontario, London, ON, Canada
2. School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3. School of Allied Medical Sciences, Hamadan University of Medical Sciences, Hamadan, Iran
4. Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine (SATM), Tehran University of Medical Sciences (TUMS), Tehran, Iran
5. Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran
6. Department of Medical Biotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
7. Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
8. Department of Anatomy, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
9. Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, 40 Blossom Street, Boston, 02114, MA, United States
10. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, IR, Iran

Source: Cell Communication and Signaling Published:2020

Abstract

Exosomes are extracellular vesicles characterized by their size, source, release mechanism and contents. MicroRNAs (miRNAs) are single stranded non-coding RNAs transcribed from DNA. Exosomes and miRNAs are widespread in eukaryotic cells, especially in mesenchymal stem cells (MSCs). MSCs are used for tissue regeneration, and also exert paracrine, anti-inflammatory and immunomodulatory effects. However, the use of MSCs is controversial, especially in the presence or after the remission of a tumor, due to their secretion of growth factors and their migration ability. Instead of intact MSCs, MSC-derived compartments or substances could be used as practical tools for diagnosis, follow up, management and monitoring of diseases. Herein, we discuss some aspects of exosomal miRNAs derived from MSCs in the progression, diagnosis and treatment of various diseases. [MediaObject not available: see fulltext.] © 2020 The Author(s).

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Hamid Reza Mirzaei (20)

Javad Verdi (8)

Style	Citing Format
MLA	Asgarpour K, et al.. "Exosomal Micrornas Derived From Mesenchymal Stem Cells: Cell-To-Cell Messages." Cell Communication and Signaling, vol. 18, no. 1, 2020, pp. -.
APA	Asgarpour K, Shojaei Z, Amiri F, Ai J, Mahjoubintehran M, Ghasemi F, Arefnezhad R, Hamblin MR, Mirzaei H (2020). Exosomal Micrornas Derived From Mesenchymal Stem Cells: Cell-To-Cell Messages. Cell Communication and Signaling, 18(1), -.
Chicago	Asgarpour K, Shojaei Z, Amiri F, Ai J, Mahjoubintehran M, Ghasemi F, Arefnezhad R, Hamblin MR, Mirzaei H. "Exosomal Micrornas Derived From Mesenchymal Stem Cells: Cell-To-Cell Messages." Cell Communication and Signaling 18, no. 1 (2020): -.
Harvard	Asgarpour K et al. (2020) 'Exosomal Micrornas Derived From Mesenchymal Stem Cells: Cell-To-Cell Messages', Cell Communication and Signaling, 18(1), pp. -.
Vancouver	Asgarpour K, Shojaei Z, Amiri F, Ai J, Mahjoubintehran M, Ghasemi F, et al.. Exosomal Micrornas Derived From Mesenchymal Stem Cells: Cell-To-Cell Messages. Cell Communication and Signaling. 2020;18(1):-.
BibTex	@article{ author = {Asgarpour K and Shojaei Z and Amiri F and Ai J and Mahjoubintehran M and Ghasemi F and Arefnezhad R and Hamblin MR and Mirzaei H}, title = {Exosomal Micrornas Derived From Mesenchymal Stem Cells: Cell-To-Cell Messages}, journal = {Cell Communication and Signaling}, volume = {18}, number = {1}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Asgarpour K AU - Shojaei Z AU - Amiri F AU - Ai J AU - Mahjoubintehran M AU - Ghasemi F AU - Arefnezhad R AU - Hamblin MR AU - Mirzaei H TI - Exosomal Micrornas Derived From Mesenchymal Stem Cells: Cell-To-Cell Messages JO - Cell Communication and Signaling VL - 18 IS - 1 SP - EP - PY - 2020 ER -

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