Detection of Occult Hepatitis B Virus in Patients Undergoing Chemotherapy in Iran

Detection of Occult Hepatitis B Virus in Patients Undergoing Chemotherapy in Iran Publisher

Shirmast P¹ ; Shahri MA² ; Pashangzadeh S^{3, 4} ; Mirshahabi H¹ ; Samadi E¹ ; Motamed N⁵

Show Affiliations

1. Department of Microbiology and Virology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
2. Department of Biology, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran
3. Iranian Research Center of HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
5. Department of Community Medicine, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

Source: Future Virology Published:2022

Abstract

Aim: Occult hepatitis B infection (OBI) is life threatening and has a high mortality rate despite applying antiviral treatments in cancer patients. This study aimed to investigate the prevalence of OBI in patients undergoing chemotherapy in Iran. Materials & methods: A total of 342 patients undergoing chemotherapy were enrolled. OBI detection in anti-HBc positive individuals was conducted using nested PCR. Results: Among 342 subjects, 103 (30.1%) were positive for anti-HBc. Fifteen (14.6%) cases of 103 anti-HBc positive samples were also positive for HBsAg. Overall, HBV DNA was positive in three (3.4%) of 88 anti-HBc subjects. Conclusion: Our results indicated that OBI might occur in almost one in 25 anti-HBc-positive patients undergoing chemotherapy. © 2021 Future Medicine Ltd.

Related Docs

View other Related Docs

1. Molecular Mechanisms Responsible for Occult Hepatitis B Virus Infection, Govaresh (2019)

2. Occult Hcv and Occult Hbv Coinfection in Iranian Human Immunodeficiency Virus-Infected Individuals, Journal of Medical Virology (2020)

3. Molecular and Serological Characterization of Occult Hepatitis B Virus Infection Among Patients With Hemophilia, Journal of Medical Virology (2019)

4. Molecular Investigation of Occult Hepatitis B Virus Infection Among Patients With Liver Cancers, International Journal of Cancer Management (2023)

5. Hepatitis B Virus Infection After Immunization: How Serious It Is? an Updated Review, Clinical and Experimental Medicine (2025)

6. Analysis of Antigenic and Conformational Changes in Hepatitis B Surface Antigen (Hbsag) Identified in Iranian Patients With Chronic Hepatitis B, Hepatitis Monthly (2017)

7. The Role of Non-Coding Rnas in the Diagnosis of Different Stages (Hcc, Chb, Obi) of Hepatitis B Infection, Microbial Pathogenesis (2023)

8. Occult Hepatitis B Infection Among Hemodialysis Patients in Tabriz, Northwest of Iran: Prevalence and Mutations Within the S Region, Canadian Journal of Infectious Diseases and Medical Microbiology (2022)

Experts (# of related papers)

View all Related Experts

Seyed Mohammad Jazayeri (2)

Fereshte Ghiasvand (1)

Style	Citing Format
MLA	Shirmast P, et al.. "Detection of Occult Hepatitis B Virus in Patients Undergoing Chemotherapy in Iran." Future Virology, vol. 17, no. 1, 2022, pp. 29-36.
APA	Shirmast P, Shahri MA, Pashangzadeh S, Mirshahabi H, Samadi E, Motamed N (2022). Detection of Occult Hepatitis B Virus in Patients Undergoing Chemotherapy in Iran. Future Virology, 17(1), 29-36.
Chicago	Shirmast P, Shahri MA, Pashangzadeh S, Mirshahabi H, Samadi E, Motamed N. "Detection of Occult Hepatitis B Virus in Patients Undergoing Chemotherapy in Iran." Future Virology 17, no. 1 (2022): 29-36.
Harvard	Shirmast P et al. (2022) 'Detection of Occult Hepatitis B Virus in Patients Undergoing Chemotherapy in Iran', Future Virology, 17(1), pp. 29-36.
Vancouver	Shirmast P, Shahri MA, Pashangzadeh S, Mirshahabi H, Samadi E, Motamed N. Detection of Occult Hepatitis B Virus in Patients Undergoing Chemotherapy in Iran. Future Virology. 2022;17(1):29-36.
BibTex	@article{ author = {Shirmast P and Shahri MA and Pashangzadeh S and Mirshahabi H and Samadi E and Motamed N}, title = {Detection of Occult Hepatitis B Virus in Patients Undergoing Chemotherapy in Iran}, journal = {Future Virology}, volume = {17}, number = {1}, pages = {29-36}, year = {2022} }
RIS	TY - JOUR AU - Shirmast P AU - Shahri MA AU - Pashangzadeh S AU - Mirshahabi H AU - Samadi E AU - Motamed N TI - Detection of Occult Hepatitis B Virus in Patients Undergoing Chemotherapy in Iran JO - Future Virology VL - 17 IS - 1 SP - 29 EP - 36 PY - 2022 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract