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Dietary Supplements and Pediatric Non-Alcoholic Fatty Liver Disease: Present and the Future Publisher



Rahimlou M1 ; Ahmadnia H2 ; Hekmatdoost A3
Authors
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Authors Affiliations
  1. 1. Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, 1948141556, Iran
  2. 2. Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Shiraz University of Medical Science, Shiraz, 7417985336, Iran
  3. 3. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology, Research Institute Shahid Beheshti University of Medical Science, Tehran, 1981619573, Iran

Source: World Journal of Hepatology Published:2015


Abstract

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children. High prevalence of pediatric obesity and sedentary lifestyle has augmented the incidence of NAFLD in children. Obesity is associated with an increased risk of NAFLD through various mechanisms such as intensification of insulin resistance and increased levels of inflammatory markers. There is no approved medical intervention for treatment of pediatric NAFLD; the only proven strategy in management of pediatric NAFLD is lifestyle modification. Recently, the effects of nutritional supplements have been examined in the management of pediatric NAFLD. The purpose of this review is to summarize the studies evaluating the effects of nutritional supplements on pediatric NAFLD and explain the future direction in this field. © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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