Interleukin-6 Participation in Pathology of Ocular Diseases

Interleukin-6 Participation in Pathology of Ocular Diseases Publisher

Zahirjouzdani F^{1, 2} ; Atyabi F^{1, 2} ; Mojtabavi N³

Show Affiliations

1. Department of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Science, Tehran, Iran
2. Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, 14174, Iran
3. Department of Immunology, Iran University of Medical Sciences, Iran

Source: Pathophysiology Published:2017

Abstract

Interleukin-6 (IL-6) is a multifunctional cytokine that affects a variety of cells in the body such as osteoclasts, hepatocytes, endothelial cells, epithelial cells, white and red blood cells and etc. Elevated levels of IL-6 have been detected in many ocular diseases. Studies show that IL-6 has a major role in the pathology of glaucoma, CRVO, macular edema, ocular neovascularization, posterior capsule opacity formation, keratitis, dry eye disease, allergic eye disease, ocular autoimmune disease, corneal chemical burn, ocular inflammation and so on. IL-6 does its effects through the classic or trans-signal pathways in cells. Blocking of IL-6 signal pathways via Tocilizumab or other chemicals and therapeutics will help to overcome complications related to ocular diseases. © 2017 Elsevier B.V.

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Style	Citing Format
MLA	Zahirjouzdani F, Atyabi F, Mojtabavi N. "Interleukin-6 Participation in Pathology of Ocular Diseases." Pathophysiology, vol. 24, no. 3, 2017, pp. 123-131.
APA	Zahirjouzdani F, Atyabi F, Mojtabavi N (2017). Interleukin-6 Participation in Pathology of Ocular Diseases. Pathophysiology, 24(3), 123-131.
Chicago	Zahirjouzdani F, Atyabi F, Mojtabavi N. "Interleukin-6 Participation in Pathology of Ocular Diseases." Pathophysiology 24, no. 3 (2017): 123-131.
Harvard	Zahirjouzdani F, Atyabi F, Mojtabavi N (2017) 'Interleukin-6 Participation in Pathology of Ocular Diseases', Pathophysiology, 24(3), pp. 123-131.
Vancouver	Zahirjouzdani F, Atyabi F, Mojtabavi N. Interleukin-6 Participation in Pathology of Ocular Diseases. Pathophysiology. 2017;24(3):123-131.
BibTex	@article{ author = {Zahirjouzdani F and Atyabi F and Mojtabavi N}, title = {Interleukin-6 Participation in Pathology of Ocular Diseases}, journal = {Pathophysiology}, volume = {24}, number = {3}, pages = {123-131}, year = {2017} }
RIS	TY - JOUR AU - Zahirjouzdani F AU - Atyabi F AU - Mojtabavi N TI - Interleukin-6 Participation in Pathology of Ocular Diseases JO - Pathophysiology VL - 24 IS - 3 SP - 123 EP - 131 PY - 2017 ER -

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