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Ultrasound Nanobubbles and Their Applications As Theranostic Agents in Cancer Therapy: A Review



Ayodele AT1 ; Valizadeh A2 ; Adabi M3 ; Esnaashari SS2 ; Madani F2 ; Khosravani M2 ; Adabi M3
Authors
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Authors Affiliations
  1. 1. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, International Campus, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Young Researchers and Elite Club, Roudehen Branch, Islamic Azad University, Roudehen, Iran

Source: Biointerface Research in Applied Chemistry Published:2017

Abstract

Cancer is known as a dangerous disease at cellular and molecular level of organism which necessitates its detection and treatment in early stages. With the development of nanomedicine, the fabrication of structures/materials at the range of 1 to 100 nm offers good advantage to clinical applications. Among nanostructure, nanobubbles (NBs) have received great attention to overcomes to the limitations of low sensitivity and specificity of diagnostics and therapeutics. In addition, NBs have high potential for encapsulating and attaching therapeutic agents. Therefore, they can be used as a novel nanostructure in clinical applications. The purpose of this review is to focus on the ultrasound NBs and their applications as theranostic agents for cancer therapy. © 2017 by the authors.
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