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A Review on the Role of Lipid-Based Nanoparticles in Medical Diagnosis and Imaging Publisher Pubmed



Mirahadi M1 ; Ghanbarzadeh S2 ; Ghorbani M3 ; Gholizadeh A4 ; Hamishehkar H5
Authors
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Authors Affiliations
  1. 1. Biotechnology Research Center, Student Research Committee, Department of Medical Nanotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Cancer Gene Therapy Research Center, Zanjan Pharmaceutical Nanotechnology Research Center, Department of Pharmaceutics, Faculty of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran
  3. 3. Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Student Research Committee, Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Source: Therapeutic Delivery Published:2018


Abstract

Molecular and diagnostic imaging has been recently a subject of intense research in the treatment of numerous diseases. In medical imaging, there are different modalities with unique strengths including MRI, ultrasound imaging, computed tomography, positron emission tomography and single photon emission computed tomography. These systems need specific contrast agents to achieve a suitable image with the best quality. Nanoparticles represent an innovative tool in imaging field research and diagnostics of various diseases, especially cancerous ones. Among the nanocarriers, lipid-based nanoparticles, such as nanostructured lipid carriers, solid lipid nanoparticles and liposomes, are the most used carriers in imaging because of having many advantageous properties. This review addresses advancements in different lipid-based nanoparticles as tools in medical diagnostic and imaging. © 2018 Newlands Press.
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