Relevance Between Semen Analysis Parameters and Infertility Risk Factors: A Cross-Sectional Study in Iran Publisher



Ahmadi S¹ ; Shabani Neshati M² ; Tavoosian A³ Show Affiliations
Source: Translational Research in Urology Published:2025

Abstract

Introduction Men are involved in infertility in about 30-50% of cases. Many risk factors can cause disorders in male fertility by affecting endocrine, temperature and genetic mechanisms. Therefore, the purpose of this study is to determine the effect of infertility risk factors on changes in semen. Methods 200 infertile men were included in this study. Patients' initial information including age, sex, weight, height and were collected in data collection forms. Their semen samples were being collected to check sperm parameters according to the WHO protocol and analyzed by SPSS software. Results A total of 210 men with a mean age of 31.94±5.66 years. The mean duration of infertility in the participants in this study was 4.29±3.35 years. The mean sperm count of participants in this study was 23.21±15.49. The mean morphology index was 5.03±8.35, the mean activity index B was 10.87±7.39 and the mean activity index A was 17.85±13.86. Increasing age has a significant correlation with decreasing number, morphology index and B movement in semen. There is no significant correlation between the duration of infertility, previous history of abortion, history of scrotal surgery and disturbance of semen parameter. Activity index A was significantly higher in patients who smoked than other patients. There is no significant relationship between the history of genitourinary diseases with the number and morphology and movement indices of A. Activity index B was significantly higher in patients without genitourinary diseases. Conclusions There are controllable factors of male infertility have significant effects on semen parameter, that can be enhanced by educating and governmental supporting. On the other hand, factors such as abortion history shouldn’t cause despair such as they don’t have a significant effect on semen parameters. Further studies on larger population recommended. © 2025 Urology Research Center (URC), Tehran University of Medical Sciences.