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Monitoring of Hepatitis B Infection in the Elderly Population of Eastern Iran; [Monitorizacion De La Infeccion Por Hepatitis B En Los Sujetos Mayores De Iran Oriental] Publisher



Pagheh AS1 ; Alemzadeh E1 ; Nazar E2 ; Moodi M3 ; Sharifi F4 ; Mirimoghaddam E5 ; Rahimi MT6 ; Mohammadi S7 ; Ziaee M1
Authors
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Authors Affiliations
  1. 1. Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
  2. 2. Psychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran
  3. 3. Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran
  4. 4. Elderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Cardiovascular Diseases Research Center, Department of Molecular Medicine, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran
  6. 6. Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran
  7. 7. Department of Medical Biotechnology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran

Source: Vacunas Published:2025


Abstract

Objectives: This study aimed to investigate the prevalence of HBV infection and its associated risk factors in the elderly in Birjand. Materials and methods: The present study was a part of the community-based prospective cohort study. Subjects over 60 years of age were assessed using standard questionnaires and blood factors. The samples were tested for HBsAg by enzyme-linked immunosorbent assay. Results: Of 542 elderly people living in Birjand, 11 cases (2.03%) were positive. The median age of patients with HBsAg positive and negative was 69 (IQR: 63–77) years and 67 (IQR: 63–74) years, respectively. The results of the multiple logistic regression model showed that fatty liver disease was significantly associated with having hepatitis B (AOR (95% CI)=5.50 (1.16, 25.88)) (p < .05). However, there was no significant relationship found between variables age, sex, marital status, years of study, underlying diseases, body mass index, smoking, and blood factors with having hepatitis B (p > .05). Conclusions: Even though there were only a few positive cases, leading to a non-significant report, it is crucial to emphasize the clinical significance and health and well-being of elderly individuals contracting hepatitis B. This information can be valuable in devising suitable disease management strategies for this age group. © 2024