Long-Term Survival Rates of Patients With Nasopharyngeal Carcinoma Treated by Radiochemotherapy: A Retrospective Cohort Study

Long-Term Survival Rates of Patients With Nasopharyngeal Carcinoma Treated by Radiochemotherapy: A Retrospective Cohort Study Publisher

Kazemian A^{1, 2} ; Ghalehtaki R^{1, 2} ; Farazmand B¹ ; Taherioun M² ; Razmkhah M² ; Khalili N^{3, 4} ; Farhan F² ; Aghili M^{1, 2} ; Esmati E²

Show Affiliations

1. Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
3. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Cancer Immunology Project, Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Egyptian Journal of Otolaryngology Published:2022

Abstract

Background: Nasopharyngeal cancer (NPC) is showing an increasing incidence in Iran. Radiation is the main treatment of this cancer. Use of new techniques such as intensity-modulated radiotherapy (IMRT) is on the rise. Here, we aimed to evaluate the oncological outcomes of NPC patients treated with three-dimensional conformal radiotherapy (3DCRT) for a more reliable comparison with IMRT in the future. Results: We reviewed the medical records of 106 patients with NPC treated by definitive radiotherapy from 2007 to 2016. Patients were treated with 70 Gy in 2-Gy fractions. Twenty-one patients died during the follow-up period. Twenty-nine patients suffered from locoregional or distant recurrences. Of these, 6 recurred after 2 years of treatment completion. The 2-year and 5-year overall survival rates were 81% and 76%, respectively. The 2-year and 5-year progression-free survival rates were 72% and 63%, respectively. The 5-year locoregional recurrence and distant metastasis-free survival rates were 68% and 69%, respectively. Conclusion: Due to high survival rates of NPC and the importance of receiving planned total dose of RT, the treatment-related toxicity and quality of life are critical considerations both for patients during active treatment and for survivors. © 2022, The Author(s).

Style	Citing Format
MLA	Kazemian A, et al.. "Long-Term Survival Rates of Patients With Nasopharyngeal Carcinoma Treated by Radiochemotherapy: A Retrospective Cohort Study." Egyptian Journal of Otolaryngology, vol. 38, no. 1, 2022, pp. -.
APA	Kazemian A, Ghalehtaki R, Farazmand B, Taherioun M, Razmkhah M, Khalili N, Farhan F, Aghili M, Esmati E (2022). Long-Term Survival Rates of Patients With Nasopharyngeal Carcinoma Treated by Radiochemotherapy: A Retrospective Cohort Study. Egyptian Journal of Otolaryngology, 38(1), -.
Chicago	Kazemian A, Ghalehtaki R, Farazmand B, Taherioun M, Razmkhah M, Khalili N, Farhan F, Aghili M, Esmati E. "Long-Term Survival Rates of Patients With Nasopharyngeal Carcinoma Treated by Radiochemotherapy: A Retrospective Cohort Study." Egyptian Journal of Otolaryngology 38, no. 1 (2022): -.
Harvard	Kazemian A et al. (2022) 'Long-Term Survival Rates of Patients With Nasopharyngeal Carcinoma Treated by Radiochemotherapy: A Retrospective Cohort Study', Egyptian Journal of Otolaryngology, 38(1), pp. -.
Vancouver	Kazemian A, Ghalehtaki R, Farazmand B, Taherioun M, Razmkhah M, Khalili N, et al.. Long-Term Survival Rates of Patients With Nasopharyngeal Carcinoma Treated by Radiochemotherapy: A Retrospective Cohort Study. Egyptian Journal of Otolaryngology. 2022;38(1):-.
BibTex	@article{ author = {Kazemian A and Ghalehtaki R and Farazmand B and Taherioun M and Razmkhah M and Khalili N and Farhan F and Aghili M and Esmati E}, title = {Long-Term Survival Rates of Patients With Nasopharyngeal Carcinoma Treated by Radiochemotherapy: A Retrospective Cohort Study}, journal = {Egyptian Journal of Otolaryngology}, volume = {38}, number = {1}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Kazemian A AU - Ghalehtaki R AU - Farazmand B AU - Taherioun M AU - Razmkhah M AU - Khalili N AU - Farhan F AU - Aghili M AU - Esmati E TI - Long-Term Survival Rates of Patients With Nasopharyngeal Carcinoma Treated by Radiochemotherapy: A Retrospective Cohort Study JO - Egyptian Journal of Otolaryngology VL - 38 IS - 1 SP - EP - PY - 2022 ER -

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