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Can Oral Tolerance Explain the Inconsistencies Associated With Total Dietary Diversity and Colon Cancer? a Mechanistic Systematic Review Publisher Pubmed



Jabbari M1 ; Barati M2 ; Fathollahi A3 ; Javanmardi F4 ; Hemmati F4 ; Farahmand F5 ; Mirmiran P6 ; Einizinab H7 ; Mousavi Khaneghah A8
Authors
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Authors Affiliations
  1. 1. Faculty of Nutrition Sciences and Food Technology, Department of Community Nutrition, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Department of Cellular and Molecular Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Department of Immunology, School of Medicine, Prevention of Cardiovascular Disease Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Food Science and Technology, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Nutrition and Endocrine Research Center, Research Institute for Endocrine Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  7. 7. Department of Community Nutrition, School of Nutrition & Food Industry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  8. 8. Department of Food Science, Faculty of Food Engineering, University of Campinas (UNICAMP Campinas), Sao Paulo, Brazil

Source: Nutrition and Cancer Published:2021


Abstract

Among the gastrointestinal tract cancers, the risk of colon cancer is strongly dependent on dietary factors. For the first time in the current review, all the original case-control studies, associated with the correlation between total dietary diversity score and colon cancer risk, were evaluated. In this regard, three databases, including PubMed/MEDLINE, Scopus, and Web of Sciences, were investigated to retrieve the related citations from 1990 until 2019. Among the included citations, three studies were finally included. In these included studies, the dietary diversity score was evaluated with 129-item and 800-item FFQs. Findings reveal that total dietary diversity can increase the risk of colon cancer in men, but not women; while, one study using 57-item FFQ reported the beneficial association of total dietary diversity with colon cancer among men. Significant demand for conducting more research to investigate the real mechanistic effects of dietary diversity on the risk of colon cancer development was demonstrated due to the inconsistent, questionable, and incomplete findings associated with the included studies. © 2020 Taylor & Francis Group, LLC.