Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Agarose-Based Biomaterials for Advanced Drug Delivery Publisher Pubmed



Khodadadi Yazdi M1 ; Taghizadeh A2 ; Taghizadeh M2 ; Stadler FJ1 ; Farokhi M3 ; Mottaghitalab F4 ; Zarrintaj P5 ; Ramsey JD5 ; Seidi F6 ; Saeb MR2 ; Mozafari M7
Authors
Show Affiliations
Authors Affiliations
  1. 1. College of Materials Science and Engineering, Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, Shenzhen University, Shenzhen, 518060, China
  2. 2. Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  3. 3. National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran
  4. 4. Nanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. School of Chemical Engineering, Oklahoma State University, 420 Engineering North, Stillwater, 74078, OK, United States
  6. 6. Joint International Research Lab of Lignocellulosic Functional Materials, Nanjing Forestry University, Nanjing, 210037, China
  7. 7. Department of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran

Source: Journal of Controlled Release Published:2020


Abstract

Agarose is a prominent marine polysaccharide representing reversible thermogelling behavior, outstanding mechanical properties, high bioactivity, and switchable chemical reactivity for functionalization. As a result, agarose has received particular attention in the fabrication of advanced delivery systems as sophisticated carriers for therapeutic agents. The ever-growing use of agarose-based biomaterials for drug delivery systems resulted in rapid growth in the number of related publications, however still, a long way should be paved to achieve FDA approval for most of the proposed products. This review aims at a classification of agarose-based biomaterials and their derivatives applicable for controlled/targeted drug delivery purposes. Moreover, it attempts to deal with opportunities and challenges associated with the future developments ahead of agarose-based biomaterials in the realm of advanced drug delivery. Undoubtedly, this class of biomaterials needs further advancement, and a lot of critical questions have yet to be answered. © 2020
Related Docs
View other Related Docs
1. Agarose-Based Biomaterials for Tissue Engineering, Carbohydrate Polymers (2018)
2. Grafted Polysaccharides in Drug Delivery, Tailor-Made Polysaccharides in Drug Delivery (2022)
3. Cross-Linked Polysaccharides in Drug Delivery, Tailor-Made Polysaccharides in Drug Delivery (2022)
4. Poloxamer: A Versatile Tri-Block Copolymer for Biomedical Applications, Acta Biomaterialia (2020)
5. Agarose-Based Biomaterials: Opportunities and Challenges in Cartilage Tissue Engineering, Polymers (2020)
6. Mesenchymal Stem Cell Spheroids Embedded in an Injectable Thermosensitive Hydrogel: An in Situ Drug Formation Platform for Accelerated Wound Healing, ACS Biomaterials Science and Engineering (2020)
7. Injectable Cell-Laden Hydrogels for Tissue Engineering: Recent Advances and Future Opportunities, Tissue Engineering - Part A (2021)
8. Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering, Biomolecules (2019)
Experts (# of related papers)
View all Related Experts
Rassoul Dinarvand (6)
Fatameh Mottaghitalab (5)
Other Related Docs
9. Sustained Delivery of Olanzapine From Sunflower Oil-Based Polyol-Urethane Nanoparticles Synthesised Through a Cyclic Carbonate Ring-Opening Reaction, IET Nanobiotechnology (2019)
10. Conductive Biomaterials As Nerve Conduits: Recent Advances and Future Challenges, Applied Materials Today (2020)
11. Zeolite in Tissue Engineering: Opportunities and Challenges, MedComm (2020)
12. Thermo-Sensitive Polymers in Medicine: A Review, European Polymer Journal (2019)
13. Copper-Enriched Diamond-Like Carbon Coatings Promote Regeneration at the Bone–Implant Interface, Heliyon (2020)
14. Chitosan/Polyvinyl Alcohol Nanofibrous Membranes: Towards Green Super-Adsorbents for Toxic Gases, Heliyon (2019)
15. From Microporous to Mesoporous Mineral Frameworks: An Alliance Between Zeolite and Chitosan, Carbohydrate Research (2020)
16. Synthesis, Characterization and Performance Enhancement of Dry Polyaniline-Coated Neuroelectrodes for Electroencephalography Measurement, Current Applied Physics (2021)
17. Magnetic Nanoparticles in Cancer Therapy, Magnetic Nanoparticle-Based Hybrid Materials: Fundamentals and Applications (2021)
18. Niobium-Treated Titanium Implants With Improved Cellular and Molecular Activities at the Tissue-Implant Interface, Materials (2019)
19. Polydopamine Biomaterials for Skin Regeneration, ACS Biomaterials Science and Engineering (2022)
20. Chitosan in Biomedical Engineering: A Critical Review, Current Stem Cell Research and Therapy (2019)
21. Turning Toxic Nanomaterials Into a Safe and Bioactive Nanocarrier for Co-Delivery of Dox/Pcrispr, ACS Applied Bio Materials (2021)
22. Carboxymethylated Polysaccharides in Drug Delivery, Tailor-Made Polysaccharides in Drug Delivery (2022)
23. Zeolites in Drug Delivery: Progress, Challenges and Opportunities, Drug Discovery Today (2020)
24. Highly Curable Self-Healing Vitrimer-Like Cellulose-Modified Halloysite Nanotube/Epoxy Nanocomposite Coatings, Chemical Engineering Journal (2020)
25. Electroactive Bio-Epoxy Incorporated Chitosan-Oligoaniline As an Advanced Hydrogel Coating for Neural Interfaces, Progress in Organic Coatings (2019)
26. Engineering the Niche for Hair Regeneration — a Critical Review, Nanomedicine: Nanotechnology# Biology# and Medicine (2019)
27. Soft and Hard Sections From Cellulose-Reinforced Poly(Lactic Acid)-Based Food Packaging Films: A Critical Review, Food Packaging and Shelf Life (2020)
28. Nanocomposite Biomaterials Made by 3D Printing: Achievements and Challenges, Handbook of Polymer Nanocomposites for Industrial Applications (2020)
29. Biomaterials Selection for Neuroprosthetics, Current Opinion in Biomedical Engineering (2018)
30. Carboxymethyl Chitosan/Sodium Carboxymethyl Cellulose/Agarose Hydrogel Dressings Containing Silk Fibroin/Polydopamine Nanoparticles for Antibiotic Delivery, Journal of Drug Delivery Science and Technology (2023)
31. Clickable Polysaccharides for Biomedical Applications: A Comprehensive Review, Progress in Polymer Science (2022)
32. Biomedical Engineering of Polysaccharide-Based Tissue Adhesives: Recent Advances and Future Direction, Carbohydrate Polymers (2022)
33. Thermosensitive Chitosan/Poly(N-Isopropyl Acrylamide) Nanoparticles Embedded in Aniline Pentamer/Silk Fibroin/Polyacrylamide As an Electroactive Injectable Hydrogel for Healing Critical-Sized Calvarial Bone Defect in Aging Rat Model, International Journal of Biological Macromolecules (2022)
34. Conductive Hydrogels Based on Tragacanth and Silk Fibroin Containing Dopamine Functionalized Carboxyl-Capped Aniline Pentamer: Merging Hemostasis, Antibacterial, and Anti-Oxidant Properties Into a Multifunctional Hydrogel for Burn Wound Healing, International Journal of Biological Macromolecules (2024)
35. Zeolites for Theranostic Applications, Journal of Materials Chemistry B (2020)
36. Smart Stimuli-Responsive Implantable Drug Delivery Systems for Programmed and On-Demand Cancer Treatment: An Overview on the Emerging Materials, Chemical Engineering Journal (2022)
37. A Novel Electroactive Agarose-Aniline Pentamer Platform As a Potential Candidate for Neural Tissue Engineering, Scientific Reports (2017)
38. A Novel Ph-Responsive Nanoniosomal Emulsion for Sustained Release of Curcumin From a Chitosan-Based Nanocarrier: Emphasis on the Concurrent Improvement of Loading, Sustained Release, and Apoptosis Induction, Biotechnology Progress (2022)
39. Improving Curcumin Constraints With Ph-Responsive Chitosan Based Graphene Oxide/Montmorillonite Nanohybrid Modified Agarose in Breast Cancer Therapy, BioNanoScience (2024)
40. Emerging Biomedical Applications of Algal Polysaccharides, Current Pharmaceutical Design (2019)
41. Corneal Repair and Regeneration: Current Concepts and Future Directions, Frontiers in Bioengineering and Biotechnology (2019)
42. Sol-Gel Synthesis, Physico-Chemical and Biological Characterization of Cerium Oxide/Polyallylamine Nanoparticles, Polymers (2020)
43. Polysaccharide-Based Hydrogel Enriched by Epidermal Growth Factor Peptide Fragment for Improving the Wound Healing Process, Heliyon (2023)
44. Naturally Occurring Biological Macromolecules-Based Hydrogels: Potential Biomaterials for Peripheral Nerve Regeneration, International Journal of Biological Macromolecules (2020)
45. Development of 3D-Printed Biocompatible Materials for Meniscus Substitution, Cartilage Tissue and Knee Joint Biomechanics: Fundamentals# Characterization and Modelling (2023)
46. Encapsulation of Cartilage Cells, Principles of Biomaterials Encapsulation: Volume 2 (2023)
47. Self-Healable Conductive Polyurethane With the Body Temperature‐Responsive Shape Memory for Bone Tissue Engineering, Chemical Engineering Journal (2021)
48. Advanced Approaches to Regenerate Spinal Cord Injury: The Development of Cell and Tissue Engineering Therapy and Combinational Treatments, Biomedicine and Pharmacotherapy (2022)
49. Regenerative Strategies for the Consequences of Myocardial Infarction: Chronological Indication and Upcoming Visions, Biomedicine and Pharmacotherapy (2022)
50. Nanotechnology-Assisted Microfluidic Systems: From Bench to Bedside, Nanomedicine (2021)