Animal Models for Human Disease

Animal Models for Human Disease Publisher

Khorramizadeh MR^{1, 2, 3} ; Saadat F⁴

Show Affiliations

1. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
2. Zebrafish Core Facility, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran
3. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Immunology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran

Source: Animal Biotechnology: Models in Discovery and Translation Published:2020

Abstract

This chapter introduces some types of animal models which are used for better understanding the disease mechanisms and its treatment. These experimental models fall into two categories: spontaneous models and induced models. Among the diseases, rheumatoid arthritis (RA) as an autoimmune disease was considered. To study the pathogenesis of RA, we explained collagen-induced arthritis as an animal model that reflects a characteristic feature of RA patients. In addition, experimental allergic encephalomyelitis (EAE) as an experimental model for multiple sclerosis (MS) was explained in detail to represent a standard method to investigate in its mechanism, finding the way for the amelioration of this incurable neurological disorder. © 2020 Elsevier Inc. All rights reserved.

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Experts (# of related papers)

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Maassoumeh Akhlaghi Kolahroodi (1)

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Style	Citing Format
MLA	Khorramizadeh MR, Saadat F. "Animal Models for Human Disease." Animal Biotechnology: Models in Discovery and Translation, vol. , no. , 2020, pp. 153-171.
APA	Khorramizadeh MR, Saadat F (2020). Animal Models for Human Disease. Animal Biotechnology: Models in Discovery and Translation, (), 153-171.
Chicago	Khorramizadeh MR, Saadat F. "Animal Models for Human Disease." Animal Biotechnology: Models in Discovery and Translation , no. (2020): 153-171.
Harvard	Khorramizadeh MR, Saadat F (2020) 'Animal Models for Human Disease', Animal Biotechnology: Models in Discovery and Translation, (), pp. 153-171.
Vancouver	Khorramizadeh MR, Saadat F. Animal Models for Human Disease. Animal Biotechnology: Models in Discovery and Translation. 2020;():153-171.
BibTex	@article{ author = {Khorramizadeh MR and Saadat F}, title = {Animal Models for Human Disease}, journal = {Animal Biotechnology: Models in Discovery and Translation}, volume = {}, number = {}, pages = {153-171}, year = {2020} }
RIS	TY - JOUR AU - Khorramizadeh MR AU - Saadat F TI - Animal Models for Human Disease JO - Animal Biotechnology: Models in Discovery and Translation VL - IS - SP - 153 EP - 171 PY - 2020 ER -

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Abstract