Characterization of Improved Passag Polymer Gel Dosimeter Using Magnetic Resonance Imaging Publisher



Dorri Giv M¹ ; Majdaeen M² ; Yadollahi M³ ; Abbaspour S⁴ ; Sadrnia M⁵ ; Haghighi Borujeni M⁶ ; Ataei G⁷ ; Abedifirouzjah R⁸ Show Affiliations
Source: Applied Magnetic Resonance Published:2022

Abstract

Poly 2-acrylamido-2-methy-1-propanesulfonic acid sodium salt and gelatin (PASSAG) gel dosimeter has a negligible toxicity and also excellent dosimetric characteristics. Nonetheless, the main drawback of this gel dosimeter is its relatively low response–dose sensitivity. In this study, we investigated whether adding glucose into the conventional PASSAG gel dosimeter could increase the response–dose sensitivity. For this purpose, new gel dosimeters of G-PASSAG (glucose and PASSAG) were first fabricated, and then irradiated using 6 MV X-rays. The responses (R2) of gel dosimeters after irradiation were read out by a 1.5 T MRI scanner. In this regard, the R2–dose responses and the R2–dose sensitivities of conventional PASSAG and G-PASSAG gel dosimeters with 3 and 5 wt% glucose were investigated at a 0–10 Gy dose range, 15–24 °C scanning temperatures, and 1–30 days post-irradiation. The findings showed that the R2–dose sensitivities of G-PASSAG gel dosimeters with 3 and 5 wt% glucose (compared to conventional PASSAG gel dosimeter) improved by 6.70 and 27.13%, respectively. Furthermore, there were excellent linear R2–dose responses for these new gel dosimeters in a 0–10 Gy dose range. A relative stability in the R2–dose sensitivity of the gel dosimeters during 20–24 °C scanning room temperatures was also observed. Moreover, G-PASSAG gel dosimeters represented temporal stability at the R2 values during 15–30 days post-irradiation. Additionally, the improved R2–dose sensitivity over post-irradiation time varied 6.06–10.05% and 16.65–27.13% for G-PASSAG gel dosimeters with 3 and 5 wt% glucose, respectively. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.