Application of Nano-Radiosensitizers in Combination Cancer Therapy

Application of Nano-Radiosensitizers in Combination Cancer Therapy Publisher

Varzandeh M¹ ; Sabouri L^{2, 3} ; Mansouri V^{3, 4} ; Gharibshahian M^{3, 5} ; Beheshtizadeh N^{3, 6} ; Hamblin MR^{7, 8} ; Rezaei N^{8, 9, 10}

Show Affiliations

1. Department of Materials Engineering, Isfahan University of Technology, Isfahan, Iran
2. AmitisGen TECH Dev Group, Tehran, Iran
3. Regenerative Medicine Group (REMED), Universal Scientific Education and Research Network (USERN), Tehran, Iran
4. Gene Therapy Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
5. Student Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran
6. Department of Tissue Engineering, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
7. Laser Research Center, Faculty of Health Science, University of Johannesburg, Doornfontein, South Africa
8. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran
9. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
10. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Bioengineering and Translational Medicine Published:2023

Abstract

Radiosensitizers are compounds or nanostructures, which can improve the efficiency of ionizing radiation to kill cells. Radiosensitization increases the susceptibility of cancer cells to radiation-induced killing, while simultaneously reducing the potentially damaging effect on the cellular structure and function of the surrounding healthy tissues. Therefore, radiosensitizers are therapeutic agents used to boost the effectiveness of radiation treatment. The complexity and heterogeneity of cancer, and the multifactorial nature of its pathophysiology has led to many approaches to treatment. The effectiveness of each approach has been proven to some extent, but no definitive treatment to eradicate cancer has been discovered. The current review discusses a broad range of nano-radiosensitizers, summarizing possible combinations of radiosensitizing NPs with several other types of cancer therapy options, focusing on the benefits and drawbacks, challenges, and future prospects. © 2023 The Authors. Bioengineering & Translational Medicine published by Wiley Periodicals LLC on behalf of American Institute of Chemical Engineers.

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Mehdi Khoobi (7)

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Style	Citing Format
MLA	Varzandeh M, et al.. "Application of Nano-Radiosensitizers in Combination Cancer Therapy." Bioengineering and Translational Medicine, vol. 8, no. 3, 2023, pp. -.
APA	Varzandeh M, Sabouri L, Mansouri V, Gharibshahian M, Beheshtizadeh N, Hamblin MR, Rezaei N (2023). Application of Nano-Radiosensitizers in Combination Cancer Therapy. Bioengineering and Translational Medicine, 8(3), -.
Chicago	Varzandeh M, Sabouri L, Mansouri V, Gharibshahian M, Beheshtizadeh N, Hamblin MR, Rezaei N. "Application of Nano-Radiosensitizers in Combination Cancer Therapy." Bioengineering and Translational Medicine 8, no. 3 (2023): -.
Harvard	Varzandeh M et al. (2023) 'Application of Nano-Radiosensitizers in Combination Cancer Therapy', Bioengineering and Translational Medicine, 8(3), pp. -.
Vancouver	Varzandeh M, Sabouri L, Mansouri V, Gharibshahian M, Beheshtizadeh N, Hamblin MR, et al.. Application of Nano-Radiosensitizers in Combination Cancer Therapy. Bioengineering and Translational Medicine. 2023;8(3):-.
BibTex	@article{ author = {Varzandeh M and Sabouri L and Mansouri V and Gharibshahian M and Beheshtizadeh N and Hamblin MR and Rezaei N}, title = {Application of Nano-Radiosensitizers in Combination Cancer Therapy}, journal = {Bioengineering and Translational Medicine}, volume = {8}, number = {3}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Varzandeh M AU - Sabouri L AU - Mansouri V AU - Gharibshahian M AU - Beheshtizadeh N AU - Hamblin MR AU - Rezaei N TI - Application of Nano-Radiosensitizers in Combination Cancer Therapy JO - Bioengineering and Translational Medicine VL - 8 IS - 3 SP - EP - PY - 2023 ER -

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