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Review Paper: A Review of the Historical Evolutionary Process of Dryand Water Maze Tests in Rodents Publisher



Mohseni F1 ; Behnam SG2 ; Rafaiee R3
Authors
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Authors Affiliations
  1. 1. Student Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran
  2. 2. Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran
  3. 3. Department of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran

Source: Basic and Clinical Neuroscience Published:2020


Abstract

This research provides an overview of the historical advances of the maze tests that are widely used to assess the cognitive impairments in rodents. Particularly, this study focuses on the issue of learning and memory behavioral tests, including dry and water mazes. Several types of mazes have been used in this setting, but their real advantages and applications depend on the type selected by the researcher. We answered some of the basic questions that any interested researcher in such studies may be faced with. The reviewed topics are as follows: the definition of maze learning, the role of the memory in the maze learning, the differences between several types of mazes, and foremost the rationale behind the maze constructions and designs. © 2020 Iran University of Medical Sciences. All rights reserved.