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Femtosecond-Assisted Lasik Versus Prk: Comparison of 6-Month Visual Acuity and Quality Outcome for High Myopia Publisher Pubmed



Hashemi H1 ; Miraftab M1 ; Ghaffari R2 ; Asgari S3
Authors
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Authors Affiliations
  1. 1. Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran
  2. 2. Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, PO Box: 14155-6446, Tehran, Iran

Source: Eye and Contact Lens Published:2016


Abstract

Objective: To compare the results of femtosecond-assisted laser in situ keratomileusis (femto-LASIK) and photorefractive keratectomy with mitomycin C (PRK-MMC) for the correction of myopia more than 7.0 diopters (D). Methods: In this comparative nonrandomized trial, 60 eyes (30 eyes in each group) were enrolled. Patients were tested for uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction spherical equivalent, ocular and corneal aberrations, and contrast sensitivity (CS) before surgery and at 3 and 6 months postoperatively. Results: Mean preoperative myopia was -8.65±1.51 and -8.04±1.70 D in the femto-LASIK and PRK-MMC groups, respectively (P0.149). Intergroup differences in baseline indices were not statistically significant. At 6 months after surgery, UDVA showed an improving trend, but it was better in the femto-LASIK group (P0.026). CDVA in the two groups remained similarly unchanged (P0.170). For the femto-LASIK and PRK-MMC groups, the safety indices were 1.01±0.05 and 1.01±0.14 (P0.949), respectively, and the efficacy indices were 0.99±0.07 and 0.93±0.22 (P0.192), respectively. Comparing CS, only CS18 showed a significantly greater decrease in the femto-LASIK group compared with the PRK-MMC group (P0.016). Intergroup differences were not statistically significant in other spatial frequencies. Changes in the ocular and corneal higher order aberrations were not statistically different between the two groups except ocular coma, which increased in the femto-LASIK group (P0.041). Conclusion: Femto-LASIK improves UDVA better than PRK-MMC in high myopia. However, because of increased coma, the quality of vision is reduced. In other words, visual acuity outcome is better with femto-LASIK and visual quality outcome is better with PRK-MMC. © 2015 Contact Lens Association of Ophthalmologists.
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1. Femtosecond Laser-Assisted Lasik Versus Prk for High Myopia: Comparison of 18-Month Visual Acuity and Quality, International Ophthalmology (2017)
2. Matched Optical Quality Comparison of 3-Year Results of Prk-Mmc and Phakic Iol Implantation in the Correction of High Myopia, Eye (Basingstoke) (2015)
3. Photorefractive Keratectomy With Mitomycin-C for High Myopia: Three Year Follow-Up Results, Acta Medica Iranica (2017)
4. Photorefractive Keratectomy Results in Myopic Patients With Thin Cornea Eyes, Oman Journal of Ophthalmology (2015)