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Photopic, Mesopic, and Scotopic Visual Acuity After 18 Mw/Cm2 Accelerated Corneal Cross-Linking Publisher Pubmed



Asgari S1 ; Hashemi H2 ; Miraftab M2 ; Shahhoseini S2 ; Jafarzadhpur E3 ; Mehravaran S4 ; Fotouhi A1
Authors
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Authors Affiliations
  1. 1. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Noor Ophthalmology Research Center, Noor Eye Hospital, No 96 Esfandiar Boulevard, Vali asr Avenue, Tehran, Iran
  3. 3. Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran
  4. 4. Stein Eye Institute, University of California, Los Angeles, CA, United States

Source: Eye and Contact Lens Published:2018


Abstract

Objectives: One-year changes in uncorrected (UDVA) and corrected (CDVA) distance visual acuity under different lighting conditions after accelerated cross-linking (CXL) in patients with progressive keratoconus in comparison with nontreated cases. Methods: In this nonrandomized clinical trial, the sample included 50 eyes in the CXL group and 40 eyes in the control group. Visual acuity was tested under photopic (100 lux), mesopic (20 lux), and scotopic (0.5 lux) lighting conditions at 6 months and 1 year. Results: Changes in all studied variables were similar in the two groups (all P.0.05) after adjusting for age, but the 0.0260.17 logMAR reduction in scotopic UDVA in the CXL group showed a difference of marginal significance compared with the control group (P=0.061). In cases with baseline UDVA#20/40, 1-year adjusted results in the CXL and control groups were, respectively, 0.6160.34 and 0.8360.35 logMAR for photopic UDVA (P=0.021), 0.4860.22 and 0.6860.27 logMAR for mesopic UDVA (P=0.033), and 0.2160.14 and 0.2660.07 logMAR for mesopic CDVA (P=0.056). In those with baseline UDVA greater than 20/40, 1-year adjusted results in the CXL and control groups were, respectively, 0.1260.20 and 0.0660.10 logMAR for mesopic UDVA (P=0.034) and 0.1560.18 and 0.0760.06 logMAR for scotopic UDVA (P=0.024). Other vision indices showed no significant intergroup differences (all P.0.05). Conclusion: Poor vision (UDVA#20/40) keratoconus cases are more likely to achieve improved vision or a halt in its deterioration after CXL. In cases with good vision (UDVA.20/40), however, although further photopic vision impairment is halted, they may experience worse vision under mesopic and scotopic conditions. ©2017 Contact Lens Association of Ophthalmologists.
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