A Short Synthesis of 7-Amino Alkoxy Homoisoflavonoides

A Short Synthesis of 7-Amino Alkoxy Homoisoflavonoides Publisher

Asadipour A¹ ; Pourshojaei Y^{1, 2} ; Eskandari K¹ ; Foroumadi A³

Show Affiliations

1. Department of Medicinal Chemistry, Faculty of Pharmacy, Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
2. Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
3. Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: RSC Advances Published:2017

Abstract

The synthesis of novel derivatives of homoisoflavonoids as potentially interesting medicinally important heterocycles in an efficient catalytic two step route is introduced. In the first step, 7-aminoalkoxychromane-4-ones are synthesized via reaction between 7-hydroxychroman-4-one and aminoethylchlorides in the presence of potassium carbonate as a Bronsted base catalyst. In the next step, obtained 7-aminoalkoxychromane-4-ones are reacted with a wide range of arylaldehydes in the presence of hydrochloric acid as Bronsted acid catalyst to obtain homoisoflavonoids. Target products are medicinally very important heterocycles, because their analogs show cytotoxic activities towards human cancer cell lines. © 2017 The Royal Society of Chemistry.

Style	Citing Format
MLA	Asadipour A, et al.. "A Short Synthesis of 7-Amino Alkoxy Homoisoflavonoides." RSC Advances, vol. 7, no. 71, 2017, pp. 44680-44687.
APA	Asadipour A, Pourshojaei Y, Eskandari K, Foroumadi A (2017). A Short Synthesis of 7-Amino Alkoxy Homoisoflavonoides. RSC Advances, 7(71), 44680-44687.
Chicago	Asadipour A, Pourshojaei Y, Eskandari K, Foroumadi A. "A Short Synthesis of 7-Amino Alkoxy Homoisoflavonoides." RSC Advances 7, no. 71 (2017): 44680-44687.
Harvard	Asadipour A et al. (2017) 'A Short Synthesis of 7-Amino Alkoxy Homoisoflavonoides', RSC Advances, 7(71), pp. 44680-44687.
Vancouver	Asadipour A, Pourshojaei Y, Eskandari K, Foroumadi A. A Short Synthesis of 7-Amino Alkoxy Homoisoflavonoides. RSC Advances. 2017;7(71):44680-44687.
BibTex	@article{ author = {Asadipour A and Pourshojaei Y and Eskandari K and Foroumadi A}, title = {A Short Synthesis of 7-Amino Alkoxy Homoisoflavonoides}, journal = {RSC Advances}, volume = {7}, number = {71}, pages = {44680-44687}, year = {2017} }
RIS	TY - JOUR AU - Asadipour A AU - Pourshojaei Y AU - Eskandari K AU - Foroumadi A TI - A Short Synthesis of 7-Amino Alkoxy Homoisoflavonoides JO - RSC Advances VL - 7 IS - 71 SP - 44680 EP - 44687 PY - 2017 ER -

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