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Synthesis of N-, O-, and S-Heterocycles From Aryl/Alkyl Alkynyl Aldehydes Publisher



Doraghi F1 ; Mohaghegh F2 ; Qareaghaj OH3 ; Larijani B1 ; Mahdavi M1
Authors
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  3. 3. Chemistry and Chemical Engineering Research Center of Iran, Tehran, Iran

Source: RSC Advances Published:2023


Abstract

In the field of heterocyclic synthesis, alkynyl aldehydes serve as privileged reagents for cyclization reactions with other organic compounds to construct a broad spectrum of N-, O-, and S-heterocycles. Due to the immense application of heterocyclic molecules in pharmaceuticals, natural products, and material chemistry, the synthesis of such scaffolds has received wide attention. The transformations occurred under metal-catalyzed, metal-free-promoted, and visible-light-mediated systems. The present review article highlights the progress made in this field over the past two decades. © 2023 The Royal Society of Chemistry