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The Value of Fruit and Vegetable Consumption in Pediatric Migraine Publisher



Jahromi SR1 ; Ariyanfar S1 ; Rafiee P1 ; Togha M2
Authors
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Authors Affiliations
  1. 1. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Department of Nutrition, Headache Department, Iranian Center of Neurological Research, Neuroscience Institute Tehran University of Medical Sciences, Sina Hospital, Tehran, Iran

Source: Diet and Nutrition in Neurological Disorders Published:2023


Abstract

Globally, pediatric and adolescent age-groups are affected by headaches and migraine with a prevalence rate of about 54.4%–58.4% and 7.7%–9.1%, respectively. Although medications have been well studied in the prophylaxis of migraine, there is a lack of conclusive studies on the effect of nutrition on migraine headache and its characteristics (Yamanaka et al., 2020). A diet rich in fiber can modify the production of inflammatory cytokines, namely TNF-α and IL-6, by changing the gut microflora. The existing active segments found in fruits and vegetables have a positive impact on neurogenic inflammation via interactions with the neuropeptide receptors. This inflammatory mediator has been alleged to have a focal role in migraine pathophysiology (Ariyanfar et al., 2019). This chapter aims to discuss research that addresses the causal relationship between fruit and vegetable intake and pediatric migraine prophylaxis. © 2023 Elsevier Inc. All rights reserved.
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