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Managing Cancer Treatment in Patients With Renal Dysfunction: The Role of Chemotherapy Publisher Pubmed



Aghsaeifard Z1 ; Alizadeh R2
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Authors Affiliations
  1. 1. Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Anesthesiology and Intensive Care, AJA University of Medical Sciences, Tehran, Iran

Source: Anti-Cancer Agents in Medicinal Chemistry Published:2023


Abstract

Malignancy is characterized by damage to several vital organs, and utilizing chemotherapy as a treatment option can have toxic effects on healthy body tissues. Kidney function is commonly compromised by cancer and chemotherapy. These effects can be pre-renal, intrarenal, or postrenal. Tumor lysis syndrome and electrolyte disturb-ances are also common in this group of patients. Etiologies of this dysfunction are poorly understood; therefore, careful monitoring and management of renal function are required in such cases. This narrative review aimed to highlight some of the common renal abnormalities among patients receiving cancer and chemotherapy. © 2023 Bentham Science Publishers.
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