Effect of Food Intake and Ambient Air Pollution Exposure on Ankylosing Spondylitis Disease Activity

Effect of Food Intake and Ambient Air Pollution Exposure on Ankylosing Spondylitis Disease Activity Publisher Pubmed

Soleimanifar N^{1, 2, 3, 7, 8, 9} ; Nicknam MH^{1, 3, 7, 9} ; Bidad K⁴ ; Jamshidi AR⁵ ; Mahmoudi M⁵ ; Mostafaei S⁶ ; Hosseinikhah Z^{2, 8} ; Nikbin B^{1, 2, 3, 7, 8, 9}

Show Affiliations

1. Molecular immunology research center, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
3. Department of Immunology, Tehran University of Medical Sciences, Tehran, Iran
4. Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
5. Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
6. Department of Community Medicine, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
7. Molecular immunology research center, Tehran University of Medical Sciences, Tehran, Iran
8. Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
9. Department of Immunology, Tehran University of Medical Sciences, Tehran, Iran

Source: Advances in rheumatology (London# England) Published:2019

Abstract

BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by axial arthritis. The genetic-environmental factors seem to be involved in the pathogenesis of the disease and the disease debilitates patients during the most productive stages of their lives. The aim of this study was to examine the relationships between two environmental factors, diet and air pollution with disease activity and functional impairment in AS. METHODS: A case-control study was carried out. Thirty patients with AS and 30 age and sex-matched healthy controls were included. Disease scores including BASMI, BASDAI, BASFI, and BASG were calculated by means of the international Ankylosing Spondylitis Assessment working group consensus recommendations. The food intake was evaluated by semi-quantitative food frequency questionnaire (147 items FFQ). Level of air pollution indices, PM10 and PM2.5 information was obtained from the Tehran air quality control network. RESULTS: Total energy and fat intake, some vitamins (A, B1, B2, C) and mineral intake (potassium, calcium, iron, phosphorus, magnesium, zinc, copper and selenium) were significantly higher in patients with AS compared to controls. Fat component consumption especially Saturated Fat of Food was moderately correlated with BASFI score. PM2.5 long term exposure was strongly correlated with BASMI, BASFI and BASDAI scores of patients. CONCLUSION: High-fat diet and long term exposure to air pollution are associated with worse disease outcomes reported in patients with AS. This is an interesting area of investigation in AS pathogenesis and management.

Style	Citing Format
MLA	Soleimanifar N, et al.. "Effect of Food Intake and Ambient Air Pollution Exposure on Ankylosing Spondylitis Disease Activity." Advances in rheumatology (London# England), vol. 59, no. 1, 2019, pp. 9-.
APA	Soleimanifar N, Nicknam MH, Bidad K, Jamshidi AR, Mahmoudi M, Mostafaei S, Hosseinikhah Z, Nikbin B (2019). Effect of Food Intake and Ambient Air Pollution Exposure on Ankylosing Spondylitis Disease Activity. Advances in rheumatology (London# England), 59(1), 9-.
Chicago	Soleimanifar N, Nicknam MH, Bidad K, Jamshidi AR, Mahmoudi M, Mostafaei S, Hosseinikhah Z, Nikbin B. "Effect of Food Intake and Ambient Air Pollution Exposure on Ankylosing Spondylitis Disease Activity." Advances in rheumatology (London# England) 59, no. 1 (2019): 9-.
Harvard	Soleimanifar N et al. (2019) 'Effect of Food Intake and Ambient Air Pollution Exposure on Ankylosing Spondylitis Disease Activity', Advances in rheumatology (London# England), 59(1), pp. 9-.
Vancouver	Soleimanifar N, Nicknam MH, Bidad K, Jamshidi AR, Mahmoudi M, Mostafaei S, et al.. Effect of Food Intake and Ambient Air Pollution Exposure on Ankylosing Spondylitis Disease Activity. Advances in rheumatology (London# England). 2019;59(1):9-.
BibTex	@article{ author = {Soleimanifar N and Nicknam MH and Bidad K and Jamshidi AR and Mahmoudi M and Mostafaei S and Hosseinikhah Z and Nikbin B}, title = {Effect of Food Intake and Ambient Air Pollution Exposure on Ankylosing Spondylitis Disease Activity}, journal = {Advances in rheumatology (London# England)}, volume = {59}, number = {1}, pages = {9-}, year = {2019} }
RIS	TY - JOUR AU - Soleimanifar N AU - Nicknam MH AU - Bidad K AU - Jamshidi AR AU - Mahmoudi M AU - Mostafaei S AU - Hosseinikhah Z AU - Nikbin B TI - Effect of Food Intake and Ambient Air Pollution Exposure on Ankylosing Spondylitis Disease Activity JO - Advances in rheumatology (London# England) VL - 59 IS - 1 SP - 9 EP - PY - 2019 ER -

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Abstract