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2-Vinylaniline in the Synthesis of Heterocycles: Recent Advances Publisher



Doraghi F1 ; Navid H2 ; Karimian S3 ; Larijani B1 ; Mahdavi M1
Authors
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  3. 3. Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Source: Journal of Heterocyclic Chemistry Published:2024


Abstract

2-Vinylanilines are readily accessible substrates, which are undoubtedly one of the best candidates for the construction of diversely nitrogen-containing heterocyclic compounds. Owing to the amine and alkenyl groups in their structures, these frameworks offer a facile, direct, and selective synthetic method. This review describes various cyclization reactions involving 2-vinylanilines catalyzed by transition metals, or under metal-free conditions. © 2024 Wiley Periodicals LLC.