Effects of Ginger Supplementation on Anthropometric, Glycemic and Metabolic Parameters in Subjects With Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study Publisher



Rahimlou M^{1, 2} ; Yari Z³ ; Rayyani E¹ ; Keshavarz SA¹ ; Hosseini S² ; Morshedzadeh N³ ; Hekmatdoost A³
Source: Journal of Diabetes and Metabolic Disorders Published:2019

Abstract

Background: Metabolic syndrome (MetS) is one of the worldwide most chronic endocrine disorders. The disease can also lead to several other chronic disorders such as type 2 diabetes mellitus, cardiovascular diseases, renal diseases and cancers. This study aimed to evaluate the safety and efficacy of ginger powder on biochemical and anthropometric parameters in patients with MetS. Methods: This randomized controlled clinical trial was conducted on 37 patients with MetS. We supplemented the individuals with MetS with either 2 g per day ginger powder or placebo for 12 weeks. Biochemical and anthropometric parameters before and after the intervention were compared between the two groups. Results: After 12 weeks of treatment, the levels of triglyceride (TG), FBS, and insulin resistance were significantly improved in the patients receiving ginger in compare to the placebo group (P < 0·05). Moreover, significant changes were observed in terms of weight, waist circumference, LDL, HDL, total cholesterol, systolic and diastolic blood pressure and energy intake between the groups. Conclusion: In general, our findings demonstrated that the ginger supplementation offers beneficial effects on patients with MetS, at least, in part due to the modulatory effects on TG, FBS, and insulin resistance. © 2019, Springer Nature Switzerland AG.