Radiolabeled Peptides for Molecular Imaging of Apoptosis

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Radiolabeled Peptides for Molecular Imaging of Apoptosis Publisher Pubmed

Mosayebnia M¹ ; Hajiramezanali M² ; Shahhosseini S²

Show Affiliations

1. Shahid Beheshti University of Medical Sciences, Pharmaceutical Chemistry and Radiopharmacy, Iran
2. Tehran University of Medical Sciences School of Pharmacy, Iran

Source: Current Medicinal Chemistry Published:2020

Abstract

Apoptosis is a regulated cell death induced by extrinsic and intrinsic stimulants. Tracking of apoptosis provides an opportunity for the assessment of cardiovascular and neurodegenerative diseases as well as monitoring of cancer therapy at early stages. There are some key mediators in apoptosis cascade, which could be considered as specific targets for delivering imaging or therapeutic agents. The targeted radioisotope-based imaging agents are able to sensitively detect the physiological signal pathways which make them suitable for apoptosis imaging at a single-cell level. Radiopeptides take advantage of both the high sensitivity of nuclear imaging modalities and favorable features of peptide scaffolds. The aim of this study is to review the characteristics of those radiopeptides targeting apoptosis with different mechanisms. © 2020 Bentham Science Publishers.

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Style	Citing Format
MLA	Mosayebnia M, Hajiramezanali M, Shahhosseini S. "Radiolabeled Peptides for Molecular Imaging of Apoptosis." Current Medicinal Chemistry, vol. 27, no. 41, 2020, pp. 7064-7089.
APA	Mosayebnia M, Hajiramezanali M, Shahhosseini S (2020). Radiolabeled Peptides for Molecular Imaging of Apoptosis. Current Medicinal Chemistry, 27(41), 7064-7089.
Chicago	Mosayebnia M, Hajiramezanali M, Shahhosseini S. "Radiolabeled Peptides for Molecular Imaging of Apoptosis." Current Medicinal Chemistry 27, no. 41 (2020): 7064-7089.
Harvard	Mosayebnia M, Hajiramezanali M, Shahhosseini S (2020) 'Radiolabeled Peptides for Molecular Imaging of Apoptosis', Current Medicinal Chemistry, 27(41), pp. 7064-7089.
Vancouver	Mosayebnia M, Hajiramezanali M, Shahhosseini S. Radiolabeled Peptides for Molecular Imaging of Apoptosis. Current Medicinal Chemistry. 2020;27(41):7064-7089.
BibTex	@article{ author = {Mosayebnia M and Hajiramezanali M and Shahhosseini S}, title = {Radiolabeled Peptides for Molecular Imaging of Apoptosis}, journal = {Current Medicinal Chemistry}, volume = {27}, number = {41}, pages = {7064-7089}, year = {2020} }
RIS	TY - JOUR AU - Mosayebnia M AU - Hajiramezanali M AU - Shahhosseini S TI - Radiolabeled Peptides for Molecular Imaging of Apoptosis JO - Current Medicinal Chemistry VL - 27 IS - 41 SP - 7064 EP - 7089 PY - 2020 ER -

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