Apoptotic Functions of Micrornas in Pathogenesis, Diagnosis, and Treatment of Endometriosis

Apoptotic Functions of Micrornas in Pathogenesis, Diagnosis, and Treatment of Endometriosis Publisher

Taghavipour M¹ ; Sadoughi F² ; Mirzaei H² ; Yousefi B³ ; Moazzami B⁴ ; Chaichian S⁴ ; Mansournia MA⁵ ; Asemi Z²

Show Affiliations

1. Department of Gynecology and Obstetrics, Mazandaran University of Medical Sciences, Sari, Iran
2. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran
3. Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
4. Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran
5. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: Cell and Bioscience Published:2020

Abstract

MicroRNAs or miRNAs are a component of the non-coding RNAs family which is engaged in many cellular functions such as cell proliferation, apoptosis, gene expression, signaling pathways, angiogenesis, and etc. Endometriosis is a malignant gynecologic disorder occurring in women before menopausal age. Pathogenesis of this illness is still a discussion subject between the scientists but in our knowledge, microRNAs can be one of the possible involved factors. The purpose of this paper is to investigate the role of apoptotic activities of miRNAs in endometriosis. Accumulative evidence has demonstrated the role of cell proliferation, apoptosis, and invasion in the progression of these diseases. In this review, we looked into the specific role of apoptosis and its related genes and pathways in endometriosis and tied to present an explanation of how miRNAs can affect endometriosis by their apoptotic activities. What we found is that a great extent of miRNAs is involved in this illness and they are responsible for repressing apoptosis and progression of the disease. As a result, miRNAs have two different usages in endometriosis: biomarkers and potential therapeutic targets. In this review we gathered a great amount of evidence to inquire into the role of micro RNAs in inducing apoptosis and how this mechanism can be exerted for therapeutic purposes for endometriosis. © 2020 The Author(s).

Related Docs

View other Related Docs

1. Evaluation of Apoptosis and Angiogenesis in Ectopic and Eutopic Stromal Cells of Patients With Endometriosis Compared to Non-Endometriotic Controls, BMC Women's Health (2020)

2. The Role of Inflammation, Oxidative Stress, Angiogenesis, and Apoptosis in the Pathophysiology of Endometriosis: Basic Science and New Insights Based on Gene Expression, Journal of Cellular Physiology (2019)

3. Micrornas in Female Infertility: An Overview, Cell Biochemistry and Function (2021)

4. Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development, Contemporary Clinical Neuroscience (2023)

5. A Comprehensive Insight Into Apoptosis: Molecular Mechanisms, Signaling Pathways, and Modulating Therapeutics, Cancer Investigation (2025)

6. Cell Death Pathways and Viruses: Role of Micrornas, Molecular Therapy Nucleic Acids (2021)

7. Identification of Candidate Microrna Markers of Endometriosis With the Use of Next-Generation Sequencing and Quantitative Real-Time Polymerase Chain Reaction, Fertility and Sterility (2020)

8. Evaluation of Elam-1 Expression Alteration in Endometriosis, Minerva Ginecologica (2017)

Experts (# of related papers)

View all Related Experts

Hamid Reza Mirzaei (3)

Nima Rezaei (3)

Style	Citing Format
MLA	Taghavipour M, et al.. "Apoptotic Functions of Micrornas in Pathogenesis, Diagnosis, and Treatment of Endometriosis." Cell and Bioscience, vol. 10, no. 1, 2020, pp. -.
APA	Taghavipour M, Sadoughi F, Mirzaei H, Yousefi B, Moazzami B, Chaichian S, Mansournia MA, Asemi Z (2020). Apoptotic Functions of Micrornas in Pathogenesis, Diagnosis, and Treatment of Endometriosis. Cell and Bioscience, 10(1), -.
Chicago	Taghavipour M, Sadoughi F, Mirzaei H, Yousefi B, Moazzami B, Chaichian S, Mansournia MA, Asemi Z. "Apoptotic Functions of Micrornas in Pathogenesis, Diagnosis, and Treatment of Endometriosis." Cell and Bioscience 10, no. 1 (2020): -.
Harvard	Taghavipour M et al. (2020) 'Apoptotic Functions of Micrornas in Pathogenesis, Diagnosis, and Treatment of Endometriosis', Cell and Bioscience, 10(1), pp. -.
Vancouver	Taghavipour M, Sadoughi F, Mirzaei H, Yousefi B, Moazzami B, Chaichian S, et al.. Apoptotic Functions of Micrornas in Pathogenesis, Diagnosis, and Treatment of Endometriosis. Cell and Bioscience. 2020;10(1):-.
BibTex	@article{ author = {Taghavipour M and Sadoughi F and Mirzaei H and Yousefi B and Moazzami B and Chaichian S and Mansournia MA and Asemi Z}, title = {Apoptotic Functions of Micrornas in Pathogenesis, Diagnosis, and Treatment of Endometriosis}, journal = {Cell and Bioscience}, volume = {10}, number = {1}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Taghavipour M AU - Sadoughi F AU - Mirzaei H AU - Yousefi B AU - Moazzami B AU - Chaichian S AU - Mansournia MA AU - Asemi Z TI - Apoptotic Functions of Micrornas in Pathogenesis, Diagnosis, and Treatment of Endometriosis JO - Cell and Bioscience VL - 10 IS - 1 SP - EP - PY - 2020 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract