Development and Validation of Alzheimer’S Disease Animal Model for the Purpose of Regenerative Medicine

Development and Validation of Alzheimer’S Disease Animal Model for the Purpose of Regenerative Medicine Publisher Pubmed

Goodarzi P¹ ; Payab M² ; Alavimoghadam S³ ; Larijani B⁴ ; Rahim F⁵ ; Bana N⁶ ; Sarvari M⁶ ; Adibi H⁷ ; Foroughi Heravani N⁶ ; Hadavandkhani M⁶ ; Arjmand B^{3, 6}

Show Affiliations

1. Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
2. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
3. Metabolomics and Genomics Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
4. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
5. Health Research Institute, Thalassemia and Hemoglobinopathies Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
6. Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
7. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Cell and Tissue Banking Published:2019

Abstract

One of the most common age-related neurodegenerative disorders is Alzheimer’s disease which globally threatening the health of elderly people. Although there are several pharmacological and non- pharmacological treatments for Alzheimer’s disease, they can just decrease the symptoms in these diseases. In this context, cell therapy and regenerative medicine approach as the novel therapeutic strategies for neurodegenerative diseases would be important. Based on scientific research principles, using any novel therapeutic approaches before the run in clinical trials need to take preclinical (animal study) stapes. Accordingly, an animal study can improve our understanding of biological mechanisms of diseases and as an important step should adhering to ethical guidelines and standards. On the other hand, to gain suitable outcomes, it is important to check the appropriate validation of animal models. In this regard, the present review would discuss about the development and validation of appropriate AD animal models in the field of regenerative medicine. © 2019, Springer Nature B.V.

2. From Kitchen to Clinic: Pharmacotherapeutic Potential of Common Spices in Indian Cooking in Age-Related Neurological Disorders, Frontiers in Pharmacology (2022)

3. Therapeutic Potential of Stem Cells for Treatment of Neurodegenerative Diseases, Biotechnology Letters (2020)

4. The Design and Application of an Appropriate Parkinson’S Disease Animal Model in Regenerative Medicine, Advances in Experimental Medicine and Biology (2021)

5. Deep Learning Approaches for Early Prediction of Conversion From Mci to Ad Using Mri and Clinical Data: A Systematic Review, Archives of Computational Methods in Engineering (2025)

6. Anesthesia and Analgesia for Common Research Models of Adult Mice, Laboratory Animal Research (2022)

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Style	Citing Format
MLA	Goodarzi P, et al.. "Development and Validation of Alzheimer’S Disease Animal Model for the Purpose of Regenerative Medicine." Cell and Tissue Banking, vol. 20, no. 2, 2019, pp. 141-151.
APA	Goodarzi P, Payab M, Alavimoghadam S, Larijani B, Rahim F, Bana N, Sarvari M, Adibi H, Foroughi Heravani N, Hadavandkhani M, Arjmand B (2019). Development and Validation of Alzheimer’S Disease Animal Model for the Purpose of Regenerative Medicine. Cell and Tissue Banking, 20(2), 141-151.
Chicago	Goodarzi P, Payab M, Alavimoghadam S, Larijani B, Rahim F, Bana N, Sarvari M, et al.. "Development and Validation of Alzheimer’S Disease Animal Model for the Purpose of Regenerative Medicine." Cell and Tissue Banking 20, no. 2 (2019): 141-151.
Harvard	Goodarzi P et al. (2019) 'Development and Validation of Alzheimer’S Disease Animal Model for the Purpose of Regenerative Medicine', Cell and Tissue Banking, 20(2), pp. 141-151.
Vancouver	Goodarzi P, Payab M, Alavimoghadam S, Larijani B, Rahim F, Bana N, et al.. Development and Validation of Alzheimer’S Disease Animal Model for the Purpose of Regenerative Medicine. Cell and Tissue Banking. 2019;20(2):141-151.
BibTex	@article{ author = {Goodarzi P and Payab M and Alavimoghadam S and Larijani B and Rahim F and Bana N and Sarvari M and Adibi H and Foroughi Heravani N and Hadavandkhani M and Arjmand B}, title = {Development and Validation of Alzheimer’S Disease Animal Model for the Purpose of Regenerative Medicine}, journal = {Cell and Tissue Banking}, volume = {20}, number = {2}, pages = {141-151}, year = {2019} }
RIS	TY - JOUR AU - Goodarzi P AU - Payab M AU - Alavimoghadam S AU - Larijani B AU - Rahim F AU - Bana N AU - Sarvari M AU - Adibi H AU - Foroughi Heravani N AU - Hadavandkhani M AU - Arjmand B TI - Development and Validation of Alzheimer’S Disease Animal Model for the Purpose of Regenerative Medicine JO - Cell and Tissue Banking VL - 20 IS - 2 SP - 141 EP - 151 PY - 2019 ER -

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