Molecular Biology, Genetic, and Epigenetics of Ureteral Disease Publisher



A Mohammadi ABDOLREZA ; Lo Reis Leonardo OLIVEIRA
Source: Published:2024

Abstract

The urinary tract is composed of various organs, each with a specific function. These organs include the kidneys, ureters, bladder, prostate, and urethra. The kidney filters excess substances from the blood and produces urine as a waste byproduct. The ureters are two narrow tubes that connect the bladder to the kidneys. They play a vital role in removing waste products of the body as urine, from the kidneys and transporting it to the bladder. The walls of the ureters contain muscles that contract and relax, pushing urine from the kidneys to the bladder. If the ureters fail to function correctly, urine can flow back into the kidneys, leading to kidney infection and potentially impairing renal function. The ureters transfer a small amount of urine from the kidneys to the bladder approximately every 10-5seconds. Identifying genetic factors related to ureteral diseases can aid in early diagnosis, prompt lifestyle changes, or appropriate medical advice for prevention or treatment. Genetic testing can detect latent genetic mutations or structural changes that may eventually lead to disease in index cases or their offspring. © 2024 Elsevier B.V., All rights reserved.