Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Sars-Cov-2 in Domestic Cats (Felis Catus) in the Northwest of Iran: Evidence for Sars-Cov-2 Circulating Between Human and Cats Publisher Pubmed



Mohebali M1, 2 ; Hassanpour G2 ; Zainali M3 ; Gouya MM4 ; Khayatzadeh S5 ; Parsaei M5 ; Sarafraz N5 ; Hassanzadeh M5 ; Azarm A6 ; Salehivaziri M7 ; Sasani F8 ; Heidari Z9 ; Jalali T7 ; Pouriayevali MH7 Show All Authors
Authors
  1. Mohebali M1, 2
  2. Hassanpour G2
  3. Zainali M3
  4. Gouya MM4
  5. Khayatzadeh S5
  6. Parsaei M5
  7. Sarafraz N5
  8. Hassanzadeh M5
  9. Azarm A6
  10. Salehivaziri M7
  11. Sasani F8
  12. Heidari Z9
  13. Jalali T7
  14. Pouriayevali MH7
  15. Shoja Z7
  16. Ahmadi Z7
  17. Sadjadi M7
  18. Tavakoli M7
  19. Azadmanjiri S7
  20. Karami C9
  21. Zarei Z10
Show Affiliations
Authors Affiliations
  1. 1. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Center for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Zoonoses, Center of Communicable Diseases Management, Ministry of Health, Treatment and Medical Education, Tehran, Iran
  4. 4. Center of Communicable diseases management, Ministry of Health, Treatment and Medical Education, Tehran, Iran
  5. 5. Province Health Center, Tabriz University of Medical Sciences, Tabriz, Iran
  6. 6. Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. COVID-19 National Refernce Laboratoty, Pasteur Institute of Iran, Tehran, Iran
  8. 8. Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
  9. 9. Department of Microbiology, Parasitology and Immunology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
  10. 10. Meshkin-Shahr Research Station, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: Virus Research Published:2022


Abstract

This study aimed to investigate the prevalence of COVID-19 in domestic cats, focusing on the disease in the northwest of Iran and then showing the natural transmission of SARS-COV-2 circulating between domestic cats and humans. After receiving ethic codes from Tehran University of Medical Sciences (IR.TUMS.VCR.REC.1399.303) and confirmed by the Center of Communicable Diseases Control (CDC) of Iran, 124 domestic cats were collected from the homes and only one hospital of Meshkin -Shahr district from northwestern Iran where SARS-CoV-2 patients were hospitalized and quarantined during 2020. Samples were prepared from fluid materials of oropharynx and nasopharynx. All samples were tested by real-time PCR (RT-PCR) using specific genes N and ORF1ab in Pasteur Institute of Iran, and then partial sequence analyses of S gene were performed. All collected cats were kept in separated cages until SARS-COV-2 infection was confirmed with the RT-PCR. RT- PCR Ct values of 123 collected cats were ≥40; thus, all of them showed negative results, but one of the collected cats with close contact with its owner, whom confirmed SARS-CoV-2 showed positive results with gene N(Ct=30) and gene ORF1ab (Ct=32). Furthermore, the positive pet cat showed respiratory and gastro-intestinal clinical manifestations, and its owner was infected with SARS-CoV-2 two weeks ago. Cats are susceptible animals to SARS-CoV-2 infection. Epidemiological evidence showed that SARS-COV-2 is able to transmit to healthy cats due to having close contact with its owner as a reverse zoonosis. © 2022
Related Docs
View other Related Docs
1. Transmission Modes of Covid-19: A Systematic Review, Infectious Disorders - Drug Targets (2021)
2. Existing Antiviral Options Against Sars-Cov-2 Replication in Covid-19 Patients, Future Microbiology (2020)
3. Naringenin, a Flavanone With Antiviral and Anti-Inflammatory Effects: A Promising Treatment Strategy Against Covid-19, Phytotherapy Research (2020)
4. A Supporting System for Management of Patients With Inflammatory Bowel Disease During Covid-19 Outbreak: Iranian Experience-Study Protocol, Middle East Journal of Digestive Diseases (2020)
5. Virtual Screening Based on the Structure of More Than 105 Compounds Against Four Key Proteins of Sars-Cov-2: Mpro, Srbd, Rdrp, and Plpro, Informatics in Medicine Unlocked (2022)
6. Efficacy of Mrna, Adenoviral Vector, and Perfusion Protein Covid-19 Vaccines, Biomedicine and Pharmacotherapy (2022)
7. Comparative Analysis of 198 Sars-Cov-2 Genomes From Iran and West Asia, February 2020 to December 2021, Iranian Journal of Pathology (2023)
8. Sars-Cov-2: A Comprehensive Review From Pathogenicity of the Virus to Clinical Consequences, Journal of Medical Virology (2020)
Experts (# of related papers)
View all Related Experts
Nima Rezaei (5)
Anahita Sadeghi (2)
Other Related Docs
9. Antiviral Mouthwashes: Possible Benefit for Covid-19 With Evidence-Based Approach, Journal of Oral Microbiology (2020)
10. Crispr/Cas13: A Potential Therapeutic Option of Covid-19, Biomedicine and Pharmacotherapy (2020)
11. Introduction on Coronavirus Disease (Covid-19) Pandemic: The Global Challenge, Advances in Experimental Medicine and Biology (2021)
12. Covid-19 Transmission, Vulnerability, Persistence and Nanotherapy: A Review, Environmental Chemistry Letters (2021)
13. The Comparison of Knowledge, Attitude, and Performance Regarding Food Hygiene and Safety Between People With and Without a History of Covid-19 Infection, Iranian Journal of Health and Environment (2023)
14. Covid-19: Transmission, Prevention, and Potential Therapeutic Opportunities, Clinica Chimica Acta (2020)
15. Immune Responses and Pathogenesis of Sars-Cov-2 During an Outbreak in Iran: Comparison With Sars and Mers, Reviews in Medical Virology (2020)
16. A Review of Covid-19 Survival Potential in Food and Prevention Approaches, Infection# Epidemiology and Microbiology (2020)