Human Umbilical Cord Mesenchymal Stem Cells: Heralding an Effective Treatment Against Esophageal Cancer?

Human Umbilical Cord Mesenchymal Stem Cells: Heralding an Effective Treatment Against Esophageal Cancer? Publisher Pubmed

Arefnezhad R¹ ; Rezaeitazangi F² ; Roghanishahraki H³ ; Goleij P^{4, 5} ; Zare N¹ ; Motedayyen H⁶ ; Aghazadeh E^{7, 8}

Show Affiliations

1. Coenzyme R Research Institute, Tehran, Iran
2. Department of Anatomy, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran
3. Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
4. Department of Genetics, Sana Institute of Higher Education, Sari, Iran
5. International Network of Stem Cell (INSC), Universal Scientific Education and Research Network (USERN), Tehran, Iran
6. Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran
7. Department of Toxicology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
8. Department of Pharmacology-Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Source: Cell Biology International Published:2023

Abstract

Esophageal cancer (EC), as one of the leading causes of cancer-associated mortality, influences a remarkable population of subjects globally and is histologically divided into two types, comprising esophageal adenocarcinoma (EAC) and esophageal squamous cell carcinoma (ESCC). Although several therapeutic approaches are present for EC, such as radiotherapy, chemotherapy, and surgery, these options have low success with serious side effects, for example, gastrointestinal toxicity, esophagitis, and pulmonary complications. Thus, utilizing an effective tool with low side effects is urgent. Newly, mesenchymal stem cells (MSCs) have received special interest for treating diverse diseases, such as cancer. Among different sources of MSCs, human umbilical cord MSCs have notable benefits, and reports expressed that they may be effective in EC treatment. For this purpose, in this review study, we aimed to summarize evidence regarding the effects of human umbilical cord MSCs on EC with a mechanistic insight. © 2023 International Federation for Cell Biology.

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Style	Citing Format
MLA	Arefnezhad R, et al.. "Human Umbilical Cord Mesenchymal Stem Cells: Heralding an Effective Treatment Against Esophageal Cancer?." Cell Biology International, vol. 47, no. 4, 2023, pp. 714-719.
APA	Arefnezhad R, Rezaeitazangi F, Roghanishahraki H, Goleij P, Zare N, Motedayyen H, Aghazadeh E (2023). Human Umbilical Cord Mesenchymal Stem Cells: Heralding an Effective Treatment Against Esophageal Cancer?. Cell Biology International, 47(4), 714-719.
Chicago	Arefnezhad R, Rezaeitazangi F, Roghanishahraki H, Goleij P, Zare N, Motedayyen H, Aghazadeh E. "Human Umbilical Cord Mesenchymal Stem Cells: Heralding an Effective Treatment Against Esophageal Cancer?." Cell Biology International 47, no. 4 (2023): 714-719.
Harvard	Arefnezhad R et al. (2023) 'Human Umbilical Cord Mesenchymal Stem Cells: Heralding an Effective Treatment Against Esophageal Cancer?', Cell Biology International, 47(4), pp. 714-719.
Vancouver	Arefnezhad R, Rezaeitazangi F, Roghanishahraki H, Goleij P, Zare N, Motedayyen H, et al.. Human Umbilical Cord Mesenchymal Stem Cells: Heralding an Effective Treatment Against Esophageal Cancer?. Cell Biology International. 2023;47(4):714-719.
BibTex	@article{ author = {Arefnezhad R and Rezaeitazangi F and Roghanishahraki H and Goleij P and Zare N and Motedayyen H and Aghazadeh E}, title = {Human Umbilical Cord Mesenchymal Stem Cells: Heralding an Effective Treatment Against Esophageal Cancer?}, journal = {Cell Biology International}, volume = {47}, number = {4}, pages = {714-719}, year = {2023} }
RIS	TY - JOUR AU - Arefnezhad R AU - Rezaeitazangi F AU - Roghanishahraki H AU - Goleij P AU - Zare N AU - Motedayyen H AU - Aghazadeh E TI - Human Umbilical Cord Mesenchymal Stem Cells: Heralding an Effective Treatment Against Esophageal Cancer? JO - Cell Biology International VL - 47 IS - 4 SP - 714 EP - 719 PY - 2023 ER -

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