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Hypertension: Potential Player in Cardiovascular Disease Incidence in Preeclampsia Publisher Pubmed



Amini P1 ; Amrovani M2 ; Nassaj ZS3 ; Ajorlou P4 ; Pezeshgi A5 ; Ghahrodizadehabyaneh B6
Authors
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Authors Affiliations
  1. 1. Atherosclerosis Research Center, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran
  2. 2. High Institute for Education and Research in Transfusion Medicine, Tehran, Iran
  3. 3. Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran
  4. 4. Department of Medical Genetics, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
  5. 5. Internal Medicine Department, Zanjan University of Medical Sciences, Zanjan, Iran
  6. 6. Resident of Obstetrics and Gynecology, Medical Faculty, Tehran University of Medical Sciences, Tehran, Iran

Source: Cardiovascular Toxicology Published:2022


Abstract

Preeclampsia (PE) is one of the complications, that threatens pregnant mothers during pregnancy. According to studies, it accounts for 3–7% of all pregnancies, and also is effective in preterm delivery. PE is the third leading cause of death in pregnant women. High blood pressure in PE can increase the risk of developing cardiovascular disease (CVD) in cited individuals, and is one of the leading causes of death in PE individuals. Atrial natriuretic peptide (ANP), Renin-Angiotensin system and nitric oxide (NO) are some of involved factors in regulating blood pressure. Therefore, by identifying the signaling pathways, that are used by these molecules to regulate and modulate blood pressure, appropriate treatment strategies can be provided to reduce blood pressure through target therapy in PE individuals; consequently, it can reduce CVD risk and mortality. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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