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Electrocardiographic Indices and Pregnancy: A Focus on Changes Between First and Third Trimesters; [Indices Eletrocardiograficos E Gravidez: Um Foco Nas Alteracoes Entre O Primeiro E O Terceiro Trimestres] Publisher



Omidi N1 ; Khorgami M2 ; Khatami F3 ; Mahalleh M1
Authors
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Authors Affiliations
  1. 1. Cardiac Primary Prevention Research Center, Cardiovascular Disease Research Institute, Tehran Heart Center (THC), Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Community Medicine Department, Tehran University of Medical Sciences, Tehran, Iran

Source: Revista Portuguesa de Cardiologia Published:2022


Abstract

Introduction and objectives: Pregnancy can affect the cardiac conduction system, causing changes to the electrocardiographic indices that may mimic pathologic ones. The aim of this study was to discover these changes in normal pregnant women. Methods: We included 103 healthy pregnant women, aged between 18-35 years. Standard 12-lead electrocardiogram was performed in the first and third trimester and electrocardiographic indices were calculated. The patients were classified in two age categories. Results: The mean PR interval in trimester one (T1) was 133.36±20.9 ms and in third trimester (T3) was 125.03±22.6ms (p=0.046). The mean QT in T1 and T3 was 314.21±18.99 ms and 324.02±19.4 ms, respectively (p<0.001). QRS duration in T1 and T3 was 90.24±28.91 ms and 94.97±10.79 ms, respectively (p=0.027). Mean of QTc (corrected QT interval) was 384.03±23.2 in T1 and 393.20±42.48 ms in T3 (p 0.023). The difference in electrocardiogram indices between T1 and T3 was not significant within the two age groups. Conclusion: When comparing results between T1 and T3, mean parameters of electrocardiogram indices showed significant statistical differences. This will contribute insight on the approach to a number of pregnant women who complain of palpitations and visit a cardiologist. Although not statistically significant, the QT dispersion was 2% higher in participants over 30 years of age. © 2021 Sociedade Portuguesa de Cardiologia