Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Exosomal Noncoding Rnas in Prostate Cancer Publisher Pubmed



Movahedpour A1 ; Khatami SH2 ; Karami N3 ; Vakili O4 ; Naeli P5 ; Jamali Z6 ; Shabaninejad Z7 ; Tazik K8 ; Behrouj H1 ; Ghasemi H9
Authors
Show Affiliations
Authors Affiliations
  1. 1. Behbahan Faculty of Medical Sciences, Behbahan, Iran
  2. 2. Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, United Kingdom
  6. 6. Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
  8. 8. Department of General Courses, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  9. 9. Abadan University of Medical Sciences, Abadan, Iran

Source: Clinica Chimica Acta Published:2022


Abstract

Prostate cancer (PCa) is the second most common cancer and the fifth leading cause of mortality among men. The recurrent reports of false-positive results of common PCa biomarkers have led to the introduction of some promising biomarkers for PCa, such as exosomal non-coding RNAs (ncRNAs). Exosomes contain various components, such as several ncRNAs (miRNAs and lncRNAs), which are important in the initiation and progression of PCa. These ncRNAs also reflect the state of the origin cell. In this article, we reviewed research on the importance and roles of ncRNAs in PCa, focusing on exosomal ncRNAs. We highlighted plasma exosomal miRNAs (8 miRNAs), urine exosomal miRNAs (19miRNAs), serum miRNAs (2 miRNAs), and five miRNAs in semen used for PCa diagnosis. Also, four exosomal lncRNAs in plasma and urine can be used as biomarkers for PCa diagnosis. © 2022 Elsevier B.V.
Related Docs
View other Related Docs
1. Exosomal Noncoding Rnas: Key Players in Glioblastoma Drug Resistance, Molecular and Cellular Biochemistry (2021)
2. Gastrointestinal Cancer Drug Resistance: The Role of Exosomal Mirnas, Molecular Biology Reports (2022)
3. Exosomal Micrornas and Long Noncoding Rnas: Novel Mediators of Drug Resistance in Lung Cancer, Journal of Cellular Physiology (2022)
4. Liquid Biopsy in Prostate Cancer Diagnosis and Prognosis: A Narrative Review, Translational Research in Urology (2020)
5. The Landscape of Exosomal Non-Coding Rnas in Breast Cancer Drug Resistance, Focusing on Underlying Molecular Mechanisms, Frontiers in Pharmacology (2023)
6. Circulating Exosomes and Exosomal Micrornas As Biomarkers in Gastrointestinal Cancer, Cancer Gene Therapy (2017)
7. Joint Application of Biochemical Markers and Imaging Techniques in the Accurate and Early Detection of Glioblastoma, Pathology Research and Practice (2021)
8. Expression Analysis of Five Different Long Non-Coding Ribonucleic Acids in Nonsmall-Cell Lung Carcinoma Tumor and Tumor-Derived Exosomes, Diagnostics (2022)
Experts (# of related papers)
View all Related Experts
Reza Nedaeinia (2)
Rasoul Salehi (2)
Other Related Docs
9. Exosomal Mirnas As Novel Cancer Biomarkers: Challenges and Opportunities, Journal of Cellular Physiology (2018)
10. Gastric Cancer Diagnosis: From Imaging Techniques to Biochemical Biomarkers, Current Molecular Medicine (2021)
11. The Salivary Exosomal Microrna As a Potential Biomarker in Patients With Periodontitis and Oral Cancers, Chemical Biology and Drug Design (2023)
12. Epigenetic Regulation in Myocardial Infarction: Non-Coding Rnas and Exosomal Non-Coding Rnas, Frontiers in Cardiovascular Medicine (2022)
13. Electrochemical Biosensors for Early Detection of Breast Cancer, Clinica Chimica Acta (2025)
14. The Role of Cancer-Associated Fibroblasts and Exosomal Mirnas-Mediated Intercellular Communication in the Tumor Microenvironment and the Biology of Carcinogenesis: A Systematic Review, Cell Death Discovery (2024)
15. Circular Rnas and Cervical Cancer: Friends or Foes? a Landscape on Circrna-Mediated Regulation of Key Signaling Pathways Involved in the Onset and Progression of Hpv-Related Cervical Neoplasms, Cell Communication and Signaling (2024)
16. State of the Art in Microrna As Diagnostic and Therapeutic Biomarkers in Chronic Lymphocytic Leukemia, Journal of Cellular Physiology (2018)
17. Micrornas in Female Infertility: An Overview, Cell Biochemistry and Function (2021)
18. Cardiac Complications in Inherited Mitochondrial Diseases, Heart Failure Reviews (2021)
19. Glioblastoma: Exosome and Microrna As Novel Diagnosis Biomarkers, Cancer Gene Therapy (2016)
20. Micrornas and Target Molecules in Bladder Cancer, Medical Oncology (2020)
21. Biomarkers for Evaluation of Prostate Cancer Prognosis, Asian Pacific Journal of Cancer Prevention (2015)
22. Cervical Cancer Diagnosis: Insights Into Biochemical Biomarkers and Imaging Techniques, Combinatorial Chemistry and High Throughput Screening (2021)
23. Evaluation of Exosomal Mir-155, Let-7G and Let-7I Levels As a Potential Noninvasive Biomarker Among Refractory/Relapsed Patients, Responsive Patients and Patients Receiving R-Chop, Leukemia and Lymphoma (2019)
24. Early Diagnosis of Breast and Ovarian Cancers by Body Fluids Circulating Tumor-Derived Exosomes, Cancer Cell International (2020)
25. Biomarkers for Prostate Cancer Diagnosis From Genetic Perspectives, Translational Research in Urology (2020)
26. Microrna in Leukemia: Tumor Suppressors and Oncogenes With Prognostic Potential, Journal of Cellular Physiology (2019)
27. Non-Coding Rnas in Leukemia Drug Resistance: New Perspectives on Molecular Mechanisms and Signaling Pathways, Annals of Hematology (2024)
28. A Computational Framework to Infer Prostate Cancer-Associated Long Noncoding Rnas and Analyses for Identifying a Competing Endogenous Rna Network, Genetic Testing and Molecular Biomarkers (2021)
29. Interplays Between Non-Coding Rnas and Chemokines in Digestive System Cancers, Biomedicine and Pharmacotherapy (2022)
30. Differential Expression Profile of Mir-27B, Mir-29A, and Mir-155 in Chronic Lymphocytic Leukemia and Breast Cancer Patients, Molecular Therapy Oncolytics (2020)